Découvrez nos professeurs et professeures!

Arnaud Droit

Professeur titulaire

arnaud.droit@fmed.ulaval.ca

Site personnel

Département de médecine moléculaire

Centre de recherche sur le cancer

Centre de recherche du CHU de Québec - Université Laval

Centre de recherche en données massives

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Contribution à la recherche

Axe de recherche de l'Université Laval :

Santé et bien-être durables

Thématiques de recherche de la Faculté de médecine :

Bioinformatique / données massives (big data)

Domaines et intérêts de recherche du (de la) professeur(e) :

Cancer

Cancer du sein
Cancer la prostate
Environnement et cancer
Lymphomes
Nutrition et cancer
Diagnostic et détection du cancer

Neurosciences, santé mentale et toxicomanies

Génétique des maladies neurologiques et psychiatriques
Maladies neurodégénératives
Migraine
Autisme

Projets de recherche

The interplay of sex hormones and chromosomes dictates pathogenicity in progressive CNS autoimmunity - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2024-04-01 au 2029-03-31
Characterization of novel breast cancer susceptibility genes through large-scale targeted sequencing and functional assays. - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2024-04-01 au 2029-03-31
Graph-based Natural Language Querying of Integrated Biological Knowledge Databases (KibioAI) - Conseil de recherches en sciences naturelles et génie Canada - Subventions à la découverte SD (individuelles et d'équipe), chercheur principal - 2024-04-01 au 2029-03-31
National Primate Center for Pandemic Preparedness (NPCPP) - Fondation Canadienne pour l'innovation (La), Ministère de l'Économie et de l'Innovation et de l'énergie, Ministère de l'Enseignement supérieur - Fonds d'infrastructure de recherche en sciences biologiques (FIRSB), co-chercheur - 2024-03-01 au 2028-03-31
Regenerative and Sustainable Agriculture for Climate Change Adaptation and Carbon Sequestration: Rebuilding Soil Health and Increasing Crop Productivity of Canadian Potato Production Systems - Producteurs de fruits et légumes du Canada - Programme Agri-innover, chercheur principal - 2023-04-01 au 2028-03-31
Role of megakaryocytes in Systemic Lupus Erythematosus - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2023-04-01 au 2028-03-31
Caractérisation de nouveaux gènes de susceptibilité au cancer du sein - Ministère de l'Économie et de l'Innovation et de l'énergie - Programme de soutien aux organismes de recherche et d’innovation (PSO) - International Volet 2C(Ancien PSR-SIIRI), co-chercheur - 2024-02-15 au 2027-04-01
L’AIMZ-938, un nouveau promédicament anticancéreux pour le traitement des cancers du sein humain réfractaires aux traitements actuels et exprimant le cytochrome P450 1A1 - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2021-10-01 au 2026-09-30
Role of polySia in cancer immune evasion - Secrétariat Inter-Conseils (Canada) (CRSH, CRSNG, IRSC) - Réseau de centres d'excellence (RCE), University of Alberta, co-chercheur - 2024-09-01 au 2026-08-01
Chaire de recherche et d'innovation l'Oréal en biologie numérique - L'Oréal - Chaires de recherche sans organismes subventionnaires, chercheur principal - 2016-05-16 au 2026-05-15
Therapeutic approach to preserve Tfh cells and improve B cell immunity in simian immunodeficiency virus infected rhesus macaques - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2021-04-01 au 2026-03-31
Développement de nouvelles connaissances sur les cibles biologiques du 2-hexénal en vue de son utilisation comme bioherbicide - Conseil de recherches en sciences naturelles et génie Canada, Fonds de recherche du Québec - Nature et technologies - Programme NOVA- FRQNT-CRSNG pour chercheurs et chercheuses de la relève (PILOTE), Université du Québec à Trois-Rivières - UQTR, co-chercheur - 2023-03-15 au 2026-03-14
Développement de solutions diagnostiques pour les troubles neurodéveloppementaux causés par un dysfonctionnement du système Ubiquitine-Protéasome - Fonds de recherche du Québec - Santé - Appel à Projet transnationaux dans le cadre du Programme conjoint Européen sur les maladies rares (EJP RD - JTC 2022), chercheur principal - 2023-02-01 au 2026-01-31
MICROB-AI-R+, a new proteomics and AI-based technology for the detection of resistant pathogens in Urinary Tract Infections - Génome Québec - Solutions génomiques pour l’identification, la caractérisation et la surveillance de la résistance aux antimicrobiens et des pathogènes émergents, chercheur principal - 2023-10-01 au 2025-09-30
Développement de nouvelles approches immunothérapeutiques dirigées contre des néoantigènes dérivés de gènes de fusion pour le traitement de la leucémie aiguë pédiatrique - Fonds de recherche du Québec - Santé, Consortium québécois sur la découverte du médicament, CHU Sainte-Justine, Biotechnologies Neomabs Inc., Société canadienne du cancer - SynergiQc, Université de Montréal, co-chercheur - 2022-06-15 au 2025-06-14
Outil d'intelligence artificielle pour l'identification rapide et précise des micro-organismes dans le lait - Ministère de l'agriculture, des pêcheries et de l'alimentation - Innov'Action volet 1, chercheur principal - 2022-03-24 au 2025-04-30
Delineation of the epigenomic principles underlying microglial transcriptional and cellular activity in chronic neurodegenerative diseases - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2020-03-01 au 2025-03-31
Personalized ultra-fast detection and treatment of resistant microbial infections - Secrétariat des programmes interorganismes à l’intention des établissements - Nouvelles frontières en recherche, co-chercheur - 2023-03-31 au 2025-03-30
Mitochondrial mArkers To Characterize Heterogeneity in SLE (MATCH-SLE) (Planning grant) - Lupus Research Alliance - 2025 Global team science award, co-chercheur - 2024-12-01 au 2025-02-28
Biomarkers for prediction of venous thrombo-embolism in children with cancer - CHU de Québec – Université Laval – CHUL - Subvention en recherche clinique (PCRE), co-chercheur - 2024-01-23 au 2024-12-31
Développement de stratégies d'apprentissage automatisées pour déterminer les phénogroupes, la progression et les issues cliniques de la sténose valvulaire aortique - Fonds de recherche du Québec - Santé - Programme bilatéral de recherche collaborative France-Québec L'ntelligence Artificielle en santé, chercheur principal - 2022-12-06 au 2024-09-30
Nouvelle approche intégrative de génomique du microbiome pour des luzernières plus durables - Génome Québec - Programme d’intégration de la génomique, chercheur principal - 2022-05-01 au 2024-04-30
Artificial intelligence tool for fast and accurate identification of mastitis pathogenic and spoilage microorganisms in milk - Novalait inc., Consortium de recherche et innovations en bioprocédés industriels au Québec - 50e Appel de projets - spécial CRIBIQ-Novalait, chercheur principal - 2022-04-01 au 2024-03-31
Influence de l’environnement leucémique dans le développement d’évènements thrombotiques chez les enfants atteints de leucémie lymphoblastique aigue traités dans l’essai thérapeutique international prospectif DFCI 16-001 - CHU de Québec – Université Laval – CHUL - Subvention de fonctionnement de centre, co-chercheur - 2023-02-21 au 2024-03-31
Observatoire international sur les impacts sociétaux de l'intelligence artificielle et du numérique - Fonds de recherche du Québec - Société et culture, Université Laval - Fonds internes - Appel à propositions : création d’un Observatoire international sur les impacts sociétaux de l’intelligence artificielle et du numérique, co-chercheur - 2018-04-01 au 2024-03-31
Outil d'intelligence artificielle pour l'identification rapide et précise des bactéries pathogènes chez les animaux et/ou chez l'humain dans le lait et les produits laitiers - Fonds de recherche du Québec - Nature et technologies - Projet de recherche en équipe, chercheur principal - 2021-04-01 au 2024-03-31
Caractérisation de la structure 3D et de la coloration des perles chez Pinctada sp. par analyse d’image. - Institut français de recherche pour l'exploitation de la mer, chercheur principal - 2021-01-01 au 2023-12-31
Caribou Genomics : a National Non-Invasive Monitoring Approach for an Iconic and Model Species-at-Risk - Environnement Canada et Changement Climatique, Génome Canada - Programme de partenariats pour les applications de la génomique (PPAG), Trent University, co-chercheur - 2020-10-01 au 2023-09-30
Utilisation du séquençage à haut débit pour l’identification d’organismes pathogènes des plantes - Ministère de l'agriculture, des pêcheries et de l'alimentation - Prime-Vert : Programme de soutien financier, Institut de recherche et de développement en agroenvironnement, co-chercheur - 2019-08-01 au 2023-08-31
Nouvelle approche moléculaire pour la détection simultanée des virus pathogènes aux framboisiers et aux fraisiers - Ministère de l'agriculture, des pêcheries et de l'alimentation - Prime-Vert : Programme de soutien financier, Institut de recherche et de développement en agroenvironnement, co-chercheur - 2019-08-01 au 2023-08-31
Unité de recherche régionale en télésanté périnatale - Fondation Canadienne pour l'innovation (La), Ministère de la Santé et des Services sociaux - Fonds des leaders John-R.-Evans (FLJR), co-chercheur - 2022-09-01 au 2023-08-31
Development of high accuracy models for MICROB-AI, a new generation of diagnosis test for UTI - Génome Québec - Programme d’intégration de la génomique, chercheur principal - 2021-04-01 au 2023-06-30
Identifying novel molecular insights from life science massive data - Conseil de recherches en sciences naturelles et génie Canada, Secrétariat Inter-Conseils (Canada) (CRSH, CRSNG, IRSC) - Subventions à la découverte SD (individuelles et d'équipe), chercheur principal - 2018-04-01 au 2023-03-31
Cellular mechanisms regulating the pathogenesis of secondary progressive CNS autoimmunity - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2018-10-01 au 2023-03-31
Leveraging the impact of diversity in neurodevelopmental disability by integrating machine learning in personalized interventions - Instituts de recherche en santé du Canada - Canada-UK Artificial Intelligence Initiative, University of Alberta, co-chercheur - 2020-02-01 au 2023-01-31
Influence of hyperglycemia on the host-microbiome interactions during subgingival microbiome dysbiosis - Biocodex Microbiota Foundation - National Call for projects – Canada, co-chercheur - 2020-12-11 au 2022-06-10
Prevention of the immunopathology induced by SARS-CoV-2 - Instituts de recherche en santé du Canada - Subvention de fonctionnement : Possibilité de financement sur les nouveaux besoins prioritaires en recherche sur la COVID-19, co-chercheur - 2021-06-01 au 2022-05-31
Covid-19 effects on ARTErial StIffness and vascular AgiNg (CARTESIAN) study- Canada - Instituts de recherche en santé du Canada - Subvention de fonctionnement : Possibilité de financement sur les nouveaux besoins prioritaires en recherche sur la COVID-19, co-chercheur - 2021-06-01 au 2022-05-31
Dévelooppement d'algorithmes d'interprétation de modèles d'apprentissage profond pour la découverte de biomarqueurs - Fonds France Canada pour la recherche - Nouvelles collaborations de recherche, chercheur principal - 2020-04-01 au 2022-03-31
Personalized Risk Assesment for Prevention and Early Detection of Breast Cancer : Integration and Implementation (PERSPECTIVE II) - Regroupement de compagnies et corporations canadiennes, Fondation du CHU de Québec, Génome Québec, Ministère de la santé (Ontario), Ministère de l'Économie, de la Science et de l'Innovation, Instituts de recherche en santé du Canada, Fondation du cancer du sein du Québec, Génome Canada - Projets de recherche appliquée à grande échelle - Large-Scale Applied Research Project, co-chercheur - 2017-11-01 au 2022-03-31
Use of genomics to manage and protect caribou populations - Managium, Génome Québec - Programme de partenariats pour les applications de la génomique (PPAG), co-chercheur - 2018-04-01 au 2022-03-31
Une infrastructure IA multi-usagers clé en main pour gérer le cycle de vie complet des données en santé - Université Laval - Fonds internes - BDR - Cas spéciaux et obligations institutionnelles, co-chercheur - 2021-04-01 au 2021-11-30
Father's lasting influence: Molecular foundations of intergenerational transmission of the paternal environment - Instituts de recherche en santé du Canada - Subvention d'équipe : La santé des garçons et des hommes, co-chercheur - 2014-11-01 au 2021-03-31

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Publications

Effect of sitagliptin therapy on triglyceride-rich lipoprotein kinetics in patients with type 2 diabetes, Couture, P., Droit, A., Lépine, M.-C., Charest, A., Kelly, I., Lamarche, B., Tremblay, A.J., Diabetes, Obesity and Metabolism, 2014, 10.1111/dom.12359
Deletion of the MIZ-1 POZ domain increases efficacy of cytarabine treatment in T- And B-ALL/lymphoma mouse models, Moroy, T., Kosan, C., Droit, A., Winkler, R., Vadnais, C., Joly-Beauparlant, C., Fraszczak, J., Rashkovan, M., Ross, J., Cancer Research, 2019, 10.1158/0008-5472.CAN-18-3038
Early Diagnosis: End-to-End CNN–LSTM Models for Mass Spectrometry Data Classification, Arnaud Droit, Isabelle Fournier, Michel Salzet, Melissa Sanabria, Fŕed́eric Precioso, Khawla Seddiki, Analytical Chemistry, 2023, 10.1021/acs.analchem.3c00613
Influence of a pre-stimulation with chronic low-dose UVB on stress response mechanisms in human skin fibroblasts, Rochette, P.J., Droit, A., Fournier, F., Desgarnier, M.-C.D., PLoS ONE, 2017, 10.1371/journal.pone.0173740
Implementing a web-based introductory bioinformatics course for non-bioinformaticians that incorporates practical exercises, Lagüe, P., Charette, S.J., Rathier, L., Lemieux, C., Guertin, M., Gagné, S.M., Droit, A., Deveau, H., Brouard, J.-S., Bourbonnais, Y., Vincent, A.T., Biochemistry and Molecular Biology Education, 2018, 10.1002/bmb.21086
Early-Life Exposure to Environmental Contaminants Perturbs the Sperm Epigenome and Induces Negative Pregnancy Outcomes for Three Generations via the Paternal Lineage, Janice Bailey, Sarah Kimmins, Jacquetta Trasler, Arnaud Droit, Jodi Flaws, Ayelet Ziv-Gal, Nancy Côté, Donovan Chan, Serge McGraw, Marie-Pier Scott-Boyer, Astrid Deschênes, Romain Lambrot, Mathieu Dalvai, Maurice Clotilde, Epigenomes, 2021, 10.3390/epigenomes5020010
MicroRNA-132/212 deficiency enhances Aβ production and senile plaque deposition in Alzheimer's disease triple transgenic mice, Hébert, S.S., Cicchetti, F., Calon, F., Droit, A., Planel, E., Vallée, M., Saint-Pierre, M., Smith, P.Y., Dorval, V., Goupil, C., Rainone, S., Hernandez-Rapp, J., Scientific Reports, 2016, 10.1038/srep30953
Unravelling the transcriptomic landscape of the major phase II UDP-glucuronosyltransferase drug metabolizing pathway using targeted RNA sequencing, Guillemette, C., Droit, A., Lévesque, E., Villeneuve, L., Gilbert, I., Rouleau, M., Margaillan, G., Tourancheau, A., Pharmacogenomics Journal, 2016, 10.1038/tpj.2015.20
Optimizing hybrid ensemble feature selection strategies for transcriptomic biomarker discovery in complex diseases, Raluca Uricaru, Arnaud Droit, Patricia Thébault, Mickaël Leclercq, Elsa Claude, NAR Genomics and Bioinformatics, 2024, 10.1093/nargab/lqae079
iTRAQ-based quantitative proteomics of stratum corneum of dandruff scalp reveals new insights into its aetiology and similarities with atopic dermatitis, Bernard, D., Jourdain, R., El Rawadi, C., Droit, A., Bourassa, S., Donovan, M., Delattre, C., Cavusoglu, N., Archives of Dermatological Research, 2016, 10.1007/s00403-016-1681-4
timeOmics: an R package for longitudinal multi-omics data integration, Arnaud Droit, Kim-Anh Lê Cao, Olivier Perin, Marie-Pier Scott-Boyer, Antoine Bodein, Bioinformatics, 2022, 10.1093/bioinformatics/btab664
CNVs with adaptive potential in Rangifer tarandus: genome architecture and new annotated assembly, Claude Robert, Arnaud Droit, Steeve D Côté, Vincent Bourret, Joëlle Taillon, Vicky Albert, William Poisson, Isabelle Gilbert, Alexandra Carrier, Julien Prunier, Life Science Alliance, 2022, 10.26508/lsa.202101207
rMAT - An R/Bioconductor package for analyzing ChIP-chip experiments, Gottardo, R., Cheung, C., Droit, A., Bioinformatics, 2010, 10.1093/bioinformatics/btq023
New Developments and Possibilities in Reanalysis and Reinterpretation of Whole Exome Sequencing Datasets for Unsolved Rare Diseases Using Machine Learning Approaches, Arnaud Droit, Tania Cuppens, Marie-Pier Scott-Boyer, Samarth Thonta Setty, International Journal of Molecular Sciences, 2022, 10.3390/ijms23126792
Calcium Signaling Pathway Genes RUNX2 and CACNA1C Are Associated with Calcific Aortic Valve Disease, Bosse, Y., Pibarot, P., Mathieu, P., Boileau, C., Seidman, J.G., Body, S.C., Tardif, J.-C., Dube, M.-P., Arsenault, B.J., Gaudreault, N., Lavoie-Charland, E., Tremblay-Marchand, J., Lamontagne, M., Droit, A., Messika-Zeitoun, D., Guauque-Olarte, S., Circulation: Cardiovascular Genetics, 2015, 10.1161/CIRCGENETICS.115.001145
Fast and accurate bacterial species identification in urine specimens using LC-MS/MS mass spectrometry and machine learning, Droit, A., Bergeron, M.G., Bestman-Smith, J., Marcoux, J., Kelly, I., Fournier, F., Dauly, C., Arrey, T.N., Boissinot, M., Hélie, M.-C., Leclercq, M., Gotti, C., Roux-Dalvai, F., Molecular and Cellular Proteomics, 2019, 10.1074/mcp.TIR119.001559
ETumorMetastasis: A Network-based Algorithm Predicts Clinical Outcomes Using Whole-exome Sequencing Data of Cancer Patients, Edwin Wang, Arnaud Droit, Andre Nantel, Zhigang Meng, Pengyong Han, Jinfeng Zou, Naif Zaman, Chabane Tibiche, Jean-Sébastien Milanese, Genomics, Proteomics & Bioinformatics, 2021, 10.1016/j.gpb.2020.06.009
Glutamine supplementation improves the efficacy of miltefosine treatment for visceral leishmaniasis, Silvestre, R., Estaquier, J., Saha, B., Carvalho, A., Cunha, C., Droit, A., Beauparlant, C.-J., Torrado, E., Osório, N.S., Barbosa, A.M., Mesquita, I., Ferreira, C., PLoS Neglected Tropical Diseases, 2020, 10.1371/journal.pntd.0008125
Quantitative proteomic analysis of amphotericin B resistance in Leishmania infantum, Ouellette, M., Droit, A., Poirier, G.G., Légaré, D., Bourassa, S., Brotherton, M.-C., International Journal for Parasitology: Drugs and Drug Resistance, 2014, 10.1016/j.ijpddr.2014.05.002
Quality assessment of peptide tandem mass spectra, Poirier, G.G., Droit, A., Gagné, P., Wu, F.-X., BMC Bioinformatics, 2008, 10.1186/1471-2105-9-S6-S13
RNA sequencing data of human prostate cancer cells treated with androgens, Audet-Walsh, É., Droit, A., Beauparlant, C.J., Poluri, R.T.K., Data in Brief, 2019, 10.1016/j.dib.2019.104372
Bioinformatic standards for proteomics-oriented mass spectrometry, Poirier, G.G., Morissette, J., Fillon, J., Droit, A., Current Proteomics, 2006, 10.2174/157016406778194617
Resolving the temporal splenic proteome during fungal infection for discovery of putative dual perspective biomarker signatures, Jennifer Geddes-McAlister, Arnaud Droit, Florence Roux-Dalvai, Benjamin Muselius, 2023, 10.1101/2023.04.08.535756
Use of Elasticsearch based Business Intelligence tools for integration and visualization of biological data, Francois Belleau, Regis Ongaro-Carcy, Arnaud Droit, Olivier Perin, Clement Plessis, Pascal Dufour, Marie-Pier Scott-Boyer, 2023, 10.1093/bib/bbad348
Connected gene communities underlie transcriptional changes in cornelia de lange syndrome, Bilodeau, S., Droit, A., Lamaze, F.C., Vallée, M., Baguette, A., Fournier, É., Boudaoud, I., Genetics, 2017, 10.1534/genetics.117.202291
BioDiscViz: A visualization support and consensus signature selector for BioDiscML results, Arnaud Droit, Steve Bilodeau, Léopold Quitté, Mickael Leclercq, Sophiane Bouirdene, PLOS ONE, 2023, 10.1371/journal.pone.0294750
LD-annot: A Bioinformatics Tool to Automatically Provide Candidate SNPs With Annotations for Genetically Linked Genes, Droit, A., Robert, C., Porth, I., Jafarikia, M., Bastien, A., Lemaçon, A., Prunier, J., Frontiers in Genetics, 2019, 10.3389/fgene.2019.01192
Early ART reduces viral seeding and innate immunity in liver and lungs of SIV-infected macaques, Jérôme Estaquier, Ouafa Zghidi-Abouzid, Petronela Ancuta, Arnaud Droit, Mohammad-Ali Jenabian, Charles Joly Beauparlant, Calaiselvy Soundaramourty, Steven Boutrais, Gina Racine, Henintsoa Rabezanahary, Julien A. Clain, JCI Insight, 2023, 10.1172/jci.insight.167856
ASVmaker: A New Tool to Improve Taxonomic Identifications for Amplicon Sequencing Data, Richard Hogue, Arnaud Droit, Julien Vivancos, Antoine Dionne, Thomas Jeanne, Clément Plessis, Plants, 2023, 10.3390/plants12213678
Dairy product intake modifies gut microbiota composition among hyperinsulinemic individuals, Rudkowska, I., Droit, A., Gagnon, C., Weisnagel, S.J., Julien, P., O’Connor, S., Leclercq, M., Khorraminezhad, L., European Journal of Nutrition, 2021, 10.1007/s00394-020-02226-z
Extensive and accurate benchmarking of DIA acquisition methods and software tools using a complex proteomic standard, , 2020, 10.1101/2020.11.03.365585
Regulation of poly(ADP-ribose) metabolism by poly(ADP-ribose) glycohydrolase: Where and when?, Poirier, G.G., Droit, A., Haince, J.-F., Bonicalzi, M.-E., Cellular and Molecular Life Sciences, 2005, 10.1007/s00018-004-4505-1
NGS++: A library for rapid prototyping of epigenomics software tools, Gevry, N., Droit, A., Wang, S., Toupin, D., Beauparlant, C.J., Markovits, A.N., Bioinformatics, 2013, 10.1093/bioinformatics/btt312
Vitamin C alters the amount of specific endoplasmic reticulum associated proteins involved in lipid metabolism in the liver of mice synthesizing a nonfunctional werner syndrome (Wrn) mutant protein, Lebel, M., Droit, A., Kelly, I., Roux-Dalvai, F., Aumailley, L., PLoS ONE, 2018, 10.1371/journal.pone.0193170
Transcriptional signature of lymphoblastoid cell lines of BRCA1, BRCA2 and non-BRCA1/2 high risk breast cancer families, Durocher, F., Droit, A., Simard, J., Ouellette, G., Labrie, Y., Joly-Beauparlant, C., Kothari, C., Pouliot, M.-C., Oncotarget, 2017, 10.18632/oncotarget.20219
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes, Dunning, A.M., Easton, D.F., Simard, J., Chenevix-Trench, G., Antoniou, A.C., French, J.D., Kristensen, V.N., Milne, R.L., Schmidt, M.K., García-Closas, M., Chang-Claude, J., Pharoah, P.D.P., Hunter, D., Zheng, W., Zhang, Y., Yannoukakos, D., Wu, A.H., Wolk, A., Winqvist, R., Wildiers, H., Wendt, C., Weitzel, J.N., Weinberg, C.R., Wappenschmidt, B., Wang, Q., Vogel, M.J., Vijai, J., Viel, A., Vega, A., van Rensburg, E.J., van der Kolk, L.E., Vachon, C.M., Ulmer, H.-U., Tzardi, M., Tung, N., Truong, T., Troester, M.A., Torres-Mejía, G., Torres, D., Tomlinson, I., Tollenaar, R.A.E.M., Toland, A.E., Thull, D.L., Thomassen, M., Teulé, A., Terry, M.B., Teo, S.H., Tengström, M., Teixeira, M.R., Taylor, J.A., Tapper, W.J., Tan, Y.Y., Tamimi, R.M., Swerdlow, A.J., Sutter, C., Spurdle, A.B., Spinelli, J.J., Smichkoska, S., Slavin, T.P., Singer, C.F., Shu, X.-O., Shen, C.-Y., Sharma, P., Shah, M., Senter, L., Scott, R.J., Scott, C., Schürmann, P., Schöttker, B., Schoemaker, M.J., Schneeweiss, A., Schmutzler, R.K., Schmidt, D.F., Scheuner, M.T., Sawyer, E.J., Santamariña, M., Sandler, D.P., Sánchez-Herrero, E., Saloustros, E., Rossing, M., Robson, M., Romero, A., Risch, H.A., Rennert, G., Rau-Murthy, R., Rantala, J., Ramus, S.J., Radice, P., Pylkäs, K., Pujana, M.A., Prokofyeva, D., Presneau, N., Prentice, R., Prajzendanc, K., Plaseska-Karanfilska, D., Peto, J., Peterlongo, P., Peshkin, B., Peissel, B., Pedersen, I.S., Paul, J., Parsons, M.T., Park-Simon, T.-W., Park, S.K., Papp, J., Pankratz, V.S., Osorio, A., Orr, N., Olsson, H., Olopade, O.I., Olah, E., Offit, K., Norman, A., Nikitina-Zake, L., Nielsen, F.C., Neven, P., Nevanlinna, H., Neuhausen, S.L., Nathanson, K.L., Nassir, R., Narod, S.A., Muranen, T.A., Muñoz-Garzon, V.M., Mulligan, A.M., Muir, K., Moreno, F., Montagna, M., Miller, N., Miller, A., Meindl, A., McLean, C., McGuffog, L., Mayes, R., Mavroudis, D., Maurer, T., Matsuo, K., Martinez, M.E., Margolin, S., Manoukian, S., Manoochehri, M., Mannermaa, A., Makalic, E., Maishman, T., MacInnis, R.J., Lubinski, J., Loud, J.T., Long, J., Lophatananon, A., Lo, W.-Y., Lindblom, A., Lesueur, F., Lester, J., Leslie, G., Lee, E., Lambrechts, D., Laitman, Y., Kyriacou, K., Kwong, A., Kubelka-Sabit, K., Koutros, S., Kosma, V.-M., Konstantopoulou, I., Ko, Y.-D., Kitahara, C.M., Kirk, J., Kiiski, J.I., Khusnutdinova, E., Kerin, M.J., Keeman, R., Karlan, B.Y., Kapoor, P.M., Kang, D., Kaaks, R., Jung, A., Jukkola-Vuorinen, A., Jones, M.E., Johnson, N., John, E.M., Jankowitz, R.C., Janavicius, R., James, P.A., Jakubowska, A., Jakimovska, M., Jager, A., Iwasaki, M., Isaacs, C., Sachchithananthan, M., Graham, D., Pathmanathan, N., Davis, A., Carpenter, J., Yip, D., Baxter, R., Koudijs, M., Ausems, M., Oosterwijk, J., Mourits, M., van der Hout, A., de Bock, T., Mensenkamp, A., Kets, C., van den Belt-Dusebout, S., Schmidt, M., Russell, N., Rookus, M., van Leeuwen, F., Jenner, D., Hogervorst, F., Adank, M., Garcia, E.G., de Boer, M., Blok, R., van Cronenburg, T., van Asperen, C.J., Verloop, J., Siesling, S., Seynaeve, C.M., van den Ouweland, A., Obdeijn, I.-M., van Deurzen, C., Collée, M., Boere, I., Gille, H., van Engelen, K., Meijers-Heijboer, H., Aalfs, C., Antill, Y., Lakhani, S., McLachlan, S.-A., Fox, S., Edwards, S.L., Nightingale, S., Greening, S., O’Connell, S., Lok, S., Dawson, S.–J., Balleine, R., Milne, R., Scott, R., Kefford, R., Williams, R., Butow, P., Fong, P., Simpson, P., James, P., Duijf, P., Cohen, P., Pachter, N., Hayward, N., Saleh, M., Gattas, M., Friedlander, M., Field, M., Bogwitz, M., Southey, M.C., Brown, M., Price, M., Burgess, M., Wallis, M., Delatycki, M., Young, M.A., Jenkins, M., Harris, M., Gleeson, M., Cummings, M., Spurdle, M., Kentwell, M., Lobb, L., Andrews, L., Lipton, L., Phillips, K., Wu, K., Tucker, K., French, J., Kirk, J., Forbes, J., Saunus, J., Burke, J., Stone, J., Visvader, J., Kollias, J., Flanagan, J., Winship, I., Hickie, I., Gill, G., Thorne, H., Mann, G., Trench, G., Lindeman, G., Farshid, G., Macrea, F., Neidermayr, E., Haan, E., Salisbury, E., Edkins, E., Marsh, D., Amor, D., Scott, C., Hunt, C., Saunders, C., Clarke, C., Patterson, B., Meiser, B., Crook, A., Blackburn, A., Fazio, A.D., Shelling, A., Fellows, A., Spigelman, A., Trainer, A., Christian, A., Sexton, A., Imyanitov, E.N., Hulick, P.J., Huang, G., Howell, A., Hopper, J.L., Hooning, M.J., Hollestelle, A., Hogervorst, F.B.L., Hillemanns, P., Heyworth, J., Heemskerk-Gerritsen, B.A.M., Healey, C.S., He, W., Hartman, M., Hartikainen, J.M., Hamann, U., Harrington, P.A., Hall, P., Håkansson, N., Haiman, C.A., Hahnen, E., Guénel, P., Grundy, A., Gronwald, J., Grip, M., Greene, M.H., Tibiletti, M.G., González-Neira, A., Goldgar, D.E., Goldberg, M.S., Godwin, A.K., Glendon, G., Giles, G.G., Georgoulias, V., Gaudet, M.M., García-Sáenz, J.A., Garber, J., Gapstur, S.M., Ganz, P.A., Gambino, G., Gago-Dominguez, M., Frost, D., Gabrielson, M., Fritschi, L., Friedman, E., Foulkes, W.D., Foretova, L., Flyger, H., Floris, G., Fletcher, O., Fasching, P.A., Evans, D.G., Eriksson, M., Engel, C., Eccles, D.M., Dwek, M., Durcan, L., Duran, M., Dumont, M., Dubois, S., Droit, A., dos-Santos-Silva, I., Dörk, T., Domchek, S.M., Dite, G.S., Ding, Y.C., Diez, O., Devilee, P., de la Hoya, M., Daly, M.B., Czene, K., Cybulski, C., Cross, S.S., Cox, A., Couch, F.J., Cornelissen, S., Collée, J.M., Davidson, R., Eeles, R., Brennan, P., Morrison, P.J., Ahmed, M., Porteous, M.E., Rogers, M.T., Tischkowitz, M., Side, L., Izatt, L., Walker, L., Snape, K., Ong, K.-R., Barwell, J., Adlard, J., Eason, J., Cook, J., Gregory, H., Gallagher, D., Miller, C., Pottinger, C., Brewer, C., Brady, A., Murray, A., Donaldson, A., Saule, C., Moncoutier, V., Golmard, L., Gauthier-Villars, M., Fourme, E., Pauw, A.D., Colas, C., Caputo, S., Buecher, B., Belotti, M., Rouleau, E., Guillaud-Bataille, M., Caron, O., Cabaret, O., Paillerets, B.B.-D., Sobol, H., Reimineras, A., Toulas, C., Gladieff, L., Sevenet, N., Longy, M., Bubien, V., Barouk-Simonet, E., Mebirouk, N., Lesueur, F.L., Jiao, Y., Stoppa-Lyonnet, D., Fert-Ferrer, S., Leone, M., Giraud, S., Calender, A., Boutry-Kryza, N., Coulet, F., Sokolowska, J., Bronner, M., Prieur, F.P., Gesta, P., Gilbert-Dussardier, B., Chiesa, J., Delnatte, C., Bézieau, S., Venat-Bouvet, L., Leroux, D., Dreyfus, H., Faivre, L., Bertolone, G., Baurand, A., Rose, M., Bera, O., Mortemousque, I., Collonge-Rame, M.-A., Pujol, P., Coupier, I., Ingster, O., Gomes, D.M., Muller, D., Vennin, P., Révillion, F., Lasset, C., Bonadona, V., Uhrhammer, N., Bignon, Y.-J., Lallaoui, H., Vaur, D., Castera, L., Berthet, P., Mari, V., Clarke, C.L., Claes, K.B.M., Chung, W.K., Christiansen, H., Chiquette, J., Castelao, J.E., Carter, B.D., Carroll, J.S., Canzian, F., Campbell, I., Camp, N.J., Caligo, M.A., Caldés, T., Cai, Q., Buys, S.S., Burwinkel, B., Brüning, T., Brooks-Wilson, A., Brock, I.W., Briceno, I., Brenner, H., Brauch, H., Bosse, K., Borg, A., Bonanni, B., Bolla, M.K., Bojesen, S.E., Bogdanova, N.V., Blot, W., Blomqvist, C., Blanco, A.M., Bialkowska, K., Bermisheva, M., Benitez, J., Beeghly-Fadiel, A., Barrowdale, D., Barkardottir, R.B., Balmaña, J., Azzollini, J., Auer, P.L., Auber, B., Arun, B.K., Aronson, K.J., Arndt, V., Arason, A., Antonenkova, N.N., Anton-Culver, H., Andrulis, I.L., Alonso, M.R., Aittomäki, K., Agata, S., Jiang, X., Marjaneh, M.M., Ghoussaini, M., Tyrer, J.P., Lush, M., Lemaçon, A., Soucy, P., Turman, C., Michailidou, K., Dennis, J., Pooley, K.A., Kar, S., Allen, J., Barnes, D.R., Beesley, J., Aschard, H., Fachal, L., Nature Genetics, 2020, 10.1038/s41588-019-0537-1
Portrait of blood-derived extracellular vesicles in patients with Parkinson's disease, Cicchetti, F., Boilard, E., Barker, R.A., Panisset, M., Chouinard, S., Langlois, M., Dupré, N., Lacroix, S., Droit, A., Duchez, A.-C., Williams-Gray, C., Mason, S.L., Vincent, A.T., Roux-Dalvai, F., Cloutier, N., Denis, H.L., Pilon, J., Labib, R., St-Amour, I., Lamontagne-Proulx, J., Neurobiology of Disease, 2019, 10.1016/j.nbd.2018.11.002
Experimental and bioinformatic approaches for interrogating protein-protein interactions to determine protein function, Hunter, J.M., Poirier, G.G., Droit, A., Journal of Molecular Endocrinology, 2005, 10.1677/jme.1.01693
BioDiscViz : a visualization support and consensus signature selector for BioDiscML results, Arnaud Droit, Steve Bilodeau, Léopold Quitté, Mickael Leclercq, Sophiane Bouirdene, 2022, 10.1101/2022.10.07.511250
Selective and sensitive quantification of the cytochrome P450 3A4 protein in human liver homogenates through multiple reaction monitoring mass spectrometry, Barbier, O., Droit, A., Poirier, G., Milkiewicz, P., Wunsch, E., Verreault, M., Trottier, J., Kelly, I., Cieślak, A., Proteomics, 2016, 10.1002/pmic.201500386
Neutrophil-derived exosomes: A new mechanism contributing to airway smooth muscle remodeling, Lavoie, J.-P., Droit, A., Roux-Dalvai, F., Vargas, A., American Journal of Respiratory Cell and Molecular Biology, 2016, 10.1165/rcmb.2016-0033OC
An integrated pipeline for the genome-wide analysis of transcription factor binding sites from ChiP-Seq, Gottardo, R., Zhang, X., Robertson, G., Li, L., Droit, A., Mercier, E., PLoS ONE, 2011, 10.1371/journal.pone.0016432
Effects of long-term serial passaging on the characteristics and properties of cell lines derived from uveal melanoma primary tumors, Guérin, S.L., Landreville, S., Morcos, M.W., Droit, A., Fournier, F., De La Fouchardière, A., Weidmann, C., Bergeron, M.-A., Zaniolo, K., Mouriaux, F., Investigative Ophthalmology and Visual Science, 2016, 10.1167/iovs.16-19317
DSNetwork: An Integrative Approach to Visualize Predictions of Variants’ Deleteriousness, Droit, A., Simard, J., Soucy, P., Ongaro-Carcy, R., Scott-Boyer, M.-P., Lemaçon, A., Frontiers in Genetics, 2020, 10.3389/fgene.2019.01349
Proteome profiling of human epithelial ovarian cancer cell line TOV-112D, Poirier, G.G., Bourgais, D., Droit, A., Mes-Masson, A.-M., Provencher, D., Le Page, C., Kelly, I., Lemay, J.-F., Bonicalzi, M.-È., Hunter, J.M., Gagné, P., Gagné, J.-P., Molecular and Cellular Biochemistry, 2005, 10.1007/s11010-005-7556-1
Cis-regulatory hubs: a new 3D model of complex disease genetics with an application to schizophrenia, Alexandre Bureau, Steve Bilodeau, Arnaud Droit, Charles Joly-Beauparlant, Loïc Mangnier, Life Science Alliance, 2022, 10.26508/lsa.202101156
Quality assessment of peptide tandem mass spectra, Poirier, G.G., Droit, A., Gagné, P., Wu, F.-X., First International Multi- Symposiums on Computer and Computational Sciences, IMSCCS'06, 2006, 10.1109/IMSCCS.2006.109
Neuronal interleukin-1 receptors mediate pain in chronic inflammatory diseases, Lacroix, S., Sharif-Naeini, R., Boilard, E., Scherrer, G., Cicchetti, F., Droit, A., De Koninck, Y., Joly-Beauparlant, C., Bories, C., Wang, F., Pellerin, E., Turmel, R., Bretheau, F., Sotoudeh, C., Tessandier, N., Christin, M., Mailhot, B., Journal of Experimental Medicine, 2020, 10.1084/jem.20191430
KibioR & Kibio: a new architecture for next-generation data querying and sharing in big biology, Arnaud Droit, Olivier Périn, Mickael Leclercq, François Belleau, Adrien Dessemond, Marie-Pier Scott-Boyer, Régis Ongaro-Carcy, Bioinformatics, 2021, 10.1093/bioinformatics/btab157
PICS: Probabilistic Inference for ChIP-seq, Gottardo, R., Jones, S., Droit, A., Ning, K., Krzywinski, M., Robertson, G., Zhang, X., Biometrics, 2011, 10.1111/j.1541-0420.2010.01441.x
ARL13B controls male reproductive tract physiology through primary and Motile Cilia, Clémence Belleannée, Vito Mennella, Rex Hess, Kedar Narayan, Maria Agustina Battistone, Kiera Ottino, Ferran Barrachina, Arnaud Droit, Charles Joly Beauparlant, Camille Lavoie-Ouellet, Odara Medagedara, Aaran Vijayakumaran, Gabriel Campolina-Silva, Céline Augière, Communications Biology, 2024, 10.1038/s42003-024-07030-7
Cumulative learning enables convolutional neural network representations for small mass spectrometry data classification, , Nature Communication, 2020, 10.1038/s41467-020-19354-z
Large-scale automatic feature selection for biomarker discovery in high-dimensional omics data, Droit, A., Fradet, Y., Bergeron, A., Perin, O., Scott Boyer, M.P., Martin-Magniette, M.L., Vittrant, B., Leclercq, M., Frontiers in Genetics, 2019, 10.3389/fgene.2019.00452
Key intestinal genes involved in lipoprotein metabolism are downregulated in dyslipidemic men with insulin resistance, Lamarche, B., Droit, A., Lemelin, V., Kelly, I., Tremblay, A.J., Couture, P., Journal of Lipid Research, 2014, 10.1194/jlr.M040071
Establishment of a comprehensive reference transcriptome for vertebral bone tissue to study the impacts of nutritional phosphorus deficiency in rainbow trout (Oncorhynchus mykiss, Walbaum), Vandenberg, G.W., Robert, C., Droit, A., Joly Beauparlant, C., Poirier Stewart, N., Proulx, E., Deschamps, M.-H., Le Luyer, J., Marine Genomics, 2014, 10.1016/j.margen.2014.10.002
RNA expression profile of calcified bicuspid, tricuspid, and normal human aortic valves by RNA sequencing, Bossé, Y., Mathieu, P., Pibarot, P., Body, S.C., Seidman, J.G., Dagenais, F., Kalavrouziotis, D., Gaudreault, N., Tremblay-Marchand, J., Droit, A., Guauque-Olarte, S., Physiological Genomics, 2016, 10.1152/physiolgenomics.00041.2016
Triggering of NOD2 Receptor Converts Inflammatory Ly6C^high into Ly6C^low Monocytes with Patrolling Properties, Gosselin, J., Rivest, S., Brunet, A., Droit, A., Thériault, P., Préfontaine, P., Egarnes, B., LeBel, M., Lessard, A.-J., Cell Reports, 2017, 10.1016/j.celrep.2017.08.009
Proteomic investigation of phosphorylation sites in poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase, Poirier, G.G., Prigent, C., Hendzel, M.J., McDonald, D., Bourassa, S., Chevalier-Paré, M., Droit, A., Labelle, Y., Gagné, P., Moreel, X., Gagné, J.-P., Journal of Proteome Research, 2009, 10.1021/pr800810n
LY75 Ablation Mediates Mesenchymal-Epithelial Transition (MET) in Epithelial Ovarian Cancer (EOC) Cells Associated with DNA Methylation Alterations and Suppression of the Wnt/β-Catenin Pathway, Dimcho Bachvarov, Arnaud Droit, Marie-Pier Scott-Boyer, Magdalena Bachvarova, Sadia Mehdi, International Journal of Molecular Sciences, 2020, 10.3390/ijms21051848
RTANDEM, an R/Bioconductor package for MS/MS protein identification, Droit, A., Paradis, R., Joly Beauparlant, C., Fournier, F., Bioinformatics, 2014, 10.1093/bioinformatics/btu178
Comparative proteome analysis of human epithelial ovarian cancer, Poirier, G.G., Isabelle, M., Winstall, E., Droit, A., Mes-Masson, A.-M., Bonicalzi, M.-E., Mercier, G., Gagné, P., Éthier, C., Gagné, J.-P., Proteome Science, 2007, 10.1186/1477-5956-5-16
Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21, Simard, J., Nord, S., Pastinen, T., Easton, D.F., Hall, P., Kristensen, V., Pharoah, P.D.P., Dunning, A.M., Chenevix-Trench, G., Benitez, J., Zheng, W., Winqvist, R., Wang, Q., Van Den Ouweland, A.M.W., Vachon, C., Truong, T., Torres, D., Tomlinson, I., Tollenaar, R.A.E.M., Swerdlow, A., Southey, M.C., Shu, X.-O., Schmidt, M.K., Sawyer, E.J., Rudolph, A., Radice, P., Pylkäs, K., Plaseska-Karanfilska, D., Peto, J., Olswold, C., Neven, P., Nevanlinna, H., Neuhausen, S.L., Milne, R.L., Marme, F., Margolin, S., Maranian, M., Mannermaa, A., Lubinski, J., Lindblom, A., Le Marchand, L., Lambrechts, D., Kataja, V., Kabisch, M., Jones, M., Jakubowska, A., Hopper, J.L., Hooning, M.J., Hallberg, E., Hamann, U., Haiman, C.A., Haeberle, L., Guénel, P., Grenaker-Alnæs, G., González-Neira, A., Goldberg, M.S., Giles, G.G., García-Closas, M., Flyger, H., Figueroa, J., Fasching, P.A., Eriksson, M., Dos-Santos-Silva, I., Dörk, T., Devilee, P., Dennis, J., Darabi, H., Czene, K., Cross, S.S., Cox, A., Couch, F.J., Chang-Claude, J., Burwinkel, B., Broeks, A., Brenner, H., Brauch, H., Brand, J.S., Borresen-Dale, A.-L., Bonanni, B., Bolla, M.K., Bojesen, S.E., Bogdanova, N.V., Blomqvist, C., Baynes, C., Arndt, V., Anton-Culver, H., Andrulis, I.L., Droit, A., Lemaçon, A., Canisius, S., Michailidou, K., Adoue, V., Soucy, P., Hamdi, Y., Oncotarget, 2016, 10.18632/oncotarget.12818
Enhancing Classification of liquid chromatography mass spectrometry data with Batch Effect Removal Neural Networks (BERNN), Frederic Precioso, Becky Carlyle, Steven Arnold, Angus Nairn, TuKiet Lam, Weiwei Wang, Shannon Leslie, Matthijs de Geus, Florence Roux-Dalvai, Mickaël Leclerq, Simon Pelletier, Arnaud Droit, 2023, 10.21203/rs.3.rs-3112514/v1
Immune-focused multi-omics analysis of prostate cancer: leukocyte Ig-Like receptors are associated with disease progression, Droit, A., Fradet, Y., Collins, C., Boutros, P.C., Livingstone, J., Martin-Magniette, M.-L., Picard, V., Hovington, H., Légaré, X.-P., Leclercq, M., Molina, O.E., Bergeron, A., Vittrant, B., OncoImmunology, 2020, 10.1080/2162402X.2020.1851950
Investigation of male infertility using quantitative comparative proteomics, Sullivan, R., Tremblay, R., Cloutier, F., Force, A., Bourassa, S., Fournier, F., Droit, A., Légaré, C., Journal of Proteome Research, 2014, 10.1021/pr501031x
Modulating HSF1 levels impacts expression of the estrogen receptor α and antiestrogen response, Steve Bilodeau, Arnaud Droit, Maxime C Côté, Éric Fournier, Mickaël Leclercq, Tania Cuppens, Félix-Antoine Bérube-Simard, Christophe Tav, Maruhen AD Silveira, Life Science Alliance, 2021, 10.26508/lsa.202000811
metagene Profiles Analyses Reveal Regulatory Element’s Factor-Specific Recruitment Patterns, Droit, A., Bilodeau, S., Belleau, P., Lemaçon, A., Samb, R., Deschênes, A., Lamaze, F.C., Joly Beauparlant, C., PLoS Computational Biology, 2016, 10.1371/journal.pcbi.1004751
PARP-3 associates with polycomb group bodies and with components of the DNA damage repair machinery, Poirier, G.G., Hendzel, M.J., Prigent, C., Dutertre, S., Hunter, J.M., Droit, A., Ouellet, M.-E., Gagné, P., McDonald, D., Rouleau, M., Journal of Cellular Biochemistry, 2007, 10.1002/jcb.21051
Long-term Memory Testing in Children With Typical Development and Neurodevelopmental Disorders: Remote Web-based Image Task Feasibility Study, Francois V Bolduc, Jacqueline Pei, Sandra A Wiebe, Arnaud Droit, Savannah Weber, Mickael Leclercq, Kerri Hope Whitlock, Cory Scott Rosenfelt, Truong An Bui, JMIR Pediatrics and Parenting, 2023, 10.2196/39720
Association analysis identifies 65 new breast cancer risk loci, Easton, D.F., Kraft, P., Simard, J., Chenevix-Trench, G., Bader, G.D., Edwards, S.L., Dunning, A.M., Chanock, S.J., Schmidt, M.K., García-Closas, M., Milne, R.L., Hunter, D.J., Hall, P., Chang-Claude, J., Pharoah, P.D.P., Couch, F.J., Amos, C.I., Andrulis, I.L., Droit, A., Antoniou, A.C., Lakhani, S.R., Ziv, E., Ziogas, A., Zhu, B., Zheng, Y., Zheng, W., Yu, J.-C., Yoo, K.-Y., Yip, C.H., Yang, X.R., Yamaji, T., Xia, L., Wu, A.H., Wolk, A., Winqvist, R., Willett, W., Wildiers, H., Whittemore, A.S., Wendt, C., Weinberg, C.R., Wang-Gohrke, S., Waisfisz, Q., Vollenweider, J., Vincent, D., Van Der Luijt, R.B., Van Der Kolk, L., Van Den Ouweland, A.M.W., Van Den Berg, D., Van Asperen, C.J., Vachon, C., Untch, M., Ursin, G., Ulmer, H.-U., Tsugane, S., Tseng, C.-C., Truong, T., Torres, D., Tong, L., Tomlinson, I., Tollenaar, R.A.E.M., Thöne, K., Thanasitthichai, S., Tessier, D.C., Terry, M.B., Teo, S.H., Tengström, M., Taylor, J.A., Tamimi, R., Swerdlow, A., Surowy, H., Stram, D.O., Stone, J., Stewart-Brown, S., Stegmaier, C., Spinelli, J.J., Southey, M.C., Sohn, C., Smeets, A., Shu, X.-O., Shrubsole, M.J., Sherman, M.E., Sheng, G., Shen, C.-Y., Sharma, P., Shah, M., Seynaeve, C., Seal, S., Scott, C., Scott, R.J., Schürmann, P., Schumacher, F., Schoemaker, M.J., Schneeweiss, A., Schmutzler, R.K., Schmidt, D.F., Sawyer, E.J., Sangrajrang, S., Sandler, D.P., Saloustros, E., Rutgers, E.J.T., Ruebner, M., Rudolph, A., Rüdiger, T., Ruddy, K.J., Romm, J., Romero, A., Rhenius, V., Rennert, H.S., Rennert, G., Rahman, N., Radice, P., Rack, B., Pylkäs, K., Pugh, E., Prokofyeva, D., Presneau, N., Prentice, R., Plaseska-Karanfilska, D., Pinchev, M., Phillips, K.-A., Peto, J., Peterlongo, P., Perez, J.I.A., Lloyd, R., Park-Simon, T.-W., Park, S.K., Pankratz, V.S., Orr, N., Olswold, C., Olsson, H., Olson, J.E., Olopade, O.I., Norman, A., Nordestgaard, B.G., Noh, D.-Y., Nielsen, S.F., Neven, P., Nevanlinna, H., Neuhausen, 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Specific expression of novel long non-coding RNAs in high-hyperdiploid childhood acute lymphoblastic leukemia, Sinnett, D., Droit, A., Oualkacha, K., Richer, C., Vidal, R., Lafond, M.-H., Gioia, R., Ouimet, M., St-Onge, P., Caron, M., Drouin, S., Lajoie, M., PLoS ONE, 2017, 10.1371/journal.pone.0174124
A type 2 diabetes disease module with a high collective influence for Cdk2 and PTPLAD1 is localized in endosomes, Faure, R.L., Elowe, S., Droit, A., Bourassa, S., Fortier, S., Bilodeau, N., Belleau, P., Boutchueng-Djidjou, M., PLoS ONE, 2018, 10.1371/journal.pone.0205180
Identification of miR-141 as a Regulator of Epidermal Homeostasis, Claire Marionnet, Françoise Bernerd, Philippe Bastien, Martine Dumont, Arnaud Droit, Roger Rezzonico, Bernard Mari, Aude Foucher, Cécile Gastaldi, Christelle Golebiewski, Diane-Lore Vieu, Journal of Investigative Dermatology, 2024, 10.1016/j.jid.2024.10.613
Divergent Expression and Metabolic Functions of Human Glucuronosyltransferases through Alternative Splicing, Guillemette, C., Droit, A., Popa, I., Gilbert, I., Audet-Delage, Y., Duperré, A.-M., Vaucher, J., Villeneuve, L., Girard-Bock, C., Tourancheau, A., Rouleau, M., Cell Reports, 2016, 10.1016/j.celrep.2016.08.077
Increased Dairy Product Intake Alters Serum Metabolite Profiles in Subjects at Risk of Developing Type 2 Diabetes, Rudkowska, I., Bilodeau, J.-F., Droit, A., Gagnon, C., Weisnagel, S.J., Julien, P., Leclercq, M., Greffard, K., O'Connor, S., Molecular Nutrition and Food Research, 2019, 10.1002/mnfr.201900126
Fine-scale mapping of the 4q24 locus identifies & pr two Independent loci associated with breast cancer risk, Pilarski, R., Chua, K., Baynes, C., Conroy, D., Kauppila, S., Jukkola-Vuorinen, A., Pylkäs, K., Radice, P., Nickels, S., Vrieling, A., Seibold, P., Flesch-Janys, D., Karstens, J.H., Butterbach, K., Stegmaier, C., Mulot, C., Laurent-Puig, P., Raoul, Y., Le Scodan, R., Arveux, P., Kerbrat, P., Miller, N., Kerin, M., Brock, I., Balasubramanian, S., Connley, D., Cramp, H., Higham, S., Heemskerk, A., Nieuwlaat, A., Crepin, E., Bos, P., Stagner, M., Chao, P., Zatonski, W., Peplonska, B., Szeszenia-Dabrowska, N., Blom, J., Molenaar, J., Krol-Warmerdam, E., Weerasooriya, N., Selander, T., Mononen, K., Otsukka, M., Taib, N.A.M., Ching, T.Y., Lee, D., Sook-Yee, Y., Mariapun, S., Nee, K.I., Kang, P., Yee, P.S., Heguy, L., Turgeon, A., Valois, M.-F., Tranchant, M., Bernard, L., Rossi, A., Maniscalco, A., Feroce, I., Bonanni, B., Zaffaroni, D., Scuvera, G., Peissel, B., Olchers, T., Celik, M., Eilber, U., Behrens, S., Heinz, J., Obi, N., Corthouts, K., Van Brussel, T., Smeets, D., Peuteman, G., Yashiki, J., Fung, A., Whiteman, D., Hayward, N., Parsons, P., Green, A., Webb, P., Green, A., Gertig, D., De Fazio, A., Bowtell, D., Niedermayr, E., Thorne, H., Kemiläinen, H., Myöhänen, E., Christiansen, H., Hillemanns, P., Antonenkova, N., Von Smitten, K., Aaltonen, K., Erkkilä, I., Heikkinen, T., Harth, V., Lotz, A., Rabstein, S., Pesch, B., Fischer, H.-P., Baisch, C., Ko, Y.-D., Justenhoven, C., Lo, W.-Y., Hermann, V., Wolf, S., Ziegler, H., Park, H., Nelson, D., Reynolds, P., Horn-Ross, P., Schumacher, F., Lee, E., Pinder, R., Deapen, D., Clague De Hart, J., Lu, Y., Ma, H., Wang, S., Lacey, J., Bernstein, L., Álvarez, N., Bugert, P., Schneeweiß, A., Sohn, C., Jones, A., Rowan, A., Colleran, G., McInerney, N., Sargus, K., Ryder-Mills, E., Williams, E., Landrith, S., Oeser, S., Rübner, M., Schrauder, M., Siriwanarungsan, P., Boonyawongviroj, P., Hogervorst, F., Verhoef, S., Rutgers, E., Van Der Schoot, E., Maskiell, J., Angelakos, M., Meyer, J., Hilker, C.A., Windebank, S.A., Cunningham, J.M., Nielsen, S.F., Robidoux, F., La Boissière, S., Vincent, D., Bacot, F., Tessier, D.C., Luccarini, C., Dicks, E., Lee, A., Offit, K., McGuffog, L., Antoniou, A., Benlloch, S., Kote-Jarai, Z., Al Olama, A.A., Eeles, R.A., Zheng, W., Easton, D.F., Dunning, A.M., Chenevix-Trench, G., Simard, J., Pharoah, P.D.P., Hall, P., Zheng, Y., Zamora, M.P., Yip, C.H., Wu, A., Winqvist, R., Wen, W., Van Den Ouweland, A., Tseng, C.-C., Truong, T., Tomlinson, I.P.M., Tollenaar, R.A.E.M., Toland, A.E., Thienpont, B., Teo, S.H., Swerdlow, A., Southey, M.C., Shrubsole, M.J., Shi, J., Shen, C.-Y., Schmutzler, R.K., Schmidt, M.K., Sawyer, E.J., Sangrajrang, S., Rudolph, A., Putti, T.C., Peterlongo, P., Orr, N., Olson, J.E., Nord, S., Nevanlinna, H., Neuhausen, S.L., Muir, K., Meindl, A., McLean, C.A., Matsuo, K., Marme, F., Margolin, S., Manoukian, S., Mannermaa, A., Lubinski, J., Lophatananon, A., Lindblom, A., Li, J., Le Marchand, L., Lambrechts, D., Kosma, V.-M., Knight, J.A., Khan, S., Kang, D., Kabisch, M., Johnson, N., Jakubowska, A., Ito, H., Hsiung, C.-N., Hopper, J.L., Hollestelle, A., Hartman, M., Hamann, U., Haiman, C.A., Guenel, P., Grip, M., Giles, G.G., García-Closas, M., Gaborieau, V., Fostira, F., Flyger, H., Fletcher, O., Fasching, P.A., Dork, T., Droit, A., Devilee, P., Darabi, H., Czene, K., Cross, S.S., Cox, A., Couch, F.J., Choi, J.-Y., Chang-Claude, J., Canisius, S., Cai, H., Burwinkel, B., Bruning, T., Broekss, A., Brinton, L., Brenner, H., Brauch, H., Bojesen, S.E., Bogdanova, N., Blot, W., Benitez, J., Beeghly-Fadiel, A., Beckmann, M.W., Arndt, V., Anton-Culver, H., Andrulis, I.L., Kar, S.P., Beesley, J., Cai, Q., Shu, X.-O., Milne, R.L., Wang, Q., Bolla, M.K., Ghoussaini, M., Michailidou, K., Zeng, C., Long, J., Guo, X., Cancer Epidemiology Biomarkers and Prevention, 2015, 10.1158/1055-9965.EPI-15-0363
Prenatal Exposure to Environmentally-Relevant Contaminants Perturbs Male Reproductive Parameters Across Multiple Generations that are Partially Protected by Folic Acid Supplementation, Bailey, J.L., Dalvai, M., MacFarlane, A.J., Benoit-Biancamano, M.-O., Trasler, J., Kimmins, S., Droit, A., Joly-Beauparlant, C., Navarro, P., Charest, P.L., Herst, P.M., Lessard, M., Scientific Reports, 2019, 10.1038/s41598-019-50060-z
Using informative Multinomial-Dirichlet prior in a t-mixture with reversible jump estimation of nucleosome positions for genome-wide profiling, Droit, A., Lakhal-Chaieb, L., Deschênes, A., Belleau, P., Khadraoui, K., Samb, R., Statistical Applications in Genetics and Molecular Biology, 2015, 10.1515/sagmb-2014-0098
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer, Simard, J., Antoniou, A.C., Garciá-Closas, M., Chenevix-Trench, G., Kraft, P., Easton, D.F., Couch, F.J., Pharoah, P.D., Bader, G.D., Droit, A., Schmutzler, R.K., Meindl, A., Hall, P., Thomassen, M., Park, S.K., Ottini, L., Offit, K., Stone, J., Teixeira, M.R., Olsson, H., Mannermaa, A., Gago-Dominguez, M., Zorn, K.K., Ziv, E., Ziogas, A., Zhu, B., Zheng, W., Zaffaroni, D., Yannoukakos, D., Yang, X.R., Xia, L., Wu, A.H., Wolk, A., Winqvist, R., Willett, W., Wijnen, J.T., Whittemore, A.S., Wesseling, J., Wendt, C., Weitzel, J.N., Weinberg, C.R., Wappenschmidt, B., Wang-Gohrke, S., Wang, Z., Walker, L., Vollenweider, J., Vincent, D., Vijai, J., Viel, A., Vega, A., Varon-Mateeva, R., Varesco, L., Van Rensburg, E.J., Ouweland, A.M.V., Den Berg, D.V., Christi, V.A.J., Vachon, C., Ulmer, H.-U., Tyrer, J., Tung, N., Tucker, K., Truong, T., Tranchant, M., Torres, D., Tong, L., Tomlinson, I., 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Complexity of the microRNA transcriptome of cow milk and milk-derived extracellular vesicles isolated via differential ultracentrifugation, Provost, P., Droit, A., Lambert, M., Beauparlant, C.J., Laugier, J., Benmoussa, A., Journal of Dairy Science, 2020, 10.3168/jds.2019-16880
FcgRIIA expression accelerates nephritis and increases platelet activation in systemic lupus erythematosus, Boilard, E., Fortin, P.R., Lacroix, S., Rondina, M.T., Machlus, K.R., McKenzie, S.E., Droit, A., Lood, C., Rauch, J., Patey, N., Lévesque, T., Laroche, A., Zufferey, A., Salem, D., Rowley, J.W., Campbell, R.A., Cloutier, N., Mailhot, B., Tessandier, N., Allaeys, I., Melki, I., Blood, 2020, 10.1182/blood.2020004974
Folic acid supplementation reduces multigenerational sperm miRNA perturbation induced by in utero environmental contaminant exposure, , Environmental Epigenetics, 2019, 10.1093/eep/dvz024
ProPickML: Advancing Clinical Diagnostics with Automated Peak Picking in Label-Free Targeted Proteomics, Arnaud Droit, Florence Roux-Dalvai, Clarisse Gotti, Mickaël Leclercq, Elloise Coyle, Journal of Proteome Research, 2024, 10.1021/acs.jproteome.4c00689
Inferring and modeling inheritance of differentially methylated changes across multiple generations, Droit, A., Bailey, J., Kimmins, S., Dalvai, M., Lambrot, R., Scott-Boyer, M.-P., Deschênes, A., Belleau, P., Nucleic acids research, 2018, 10.1093/nar/gky362
Interactions with plant pathogens influence lipopeptides production and antimicrobial activity of Bacillus subtilis strain PTB185, Tweddell, R.J., Droit, A., Antoun, H., Nguyen, T.T.A., Kelly, I., Roux-Dalvai, F., Cossus, L., Biological Control, 2021, 10.1016/j.biocontrol.2020.104497
FOXA and master transcription factors recruit Mediator and Cohesin to the core transcriptional regulatory circuitry of cancer cells, Bilodeau, S., Droit, A., Gobeil, S., Caron, V., Joly-Beauparlant, C., Fournier, É., Côté, M.C., Lamaze, F.C., Bourriquen, G., Fournier, M., Scientific Reports, 2016, 10.1038/srep34962
Identification of a Transcriptomic Prognostic Signature by Machine Learning Using a Combination of Small Cohorts of Prostate Cancer, Droit, A., Fradet, Y., Bergeron, A., Collins, C., Martin-Magniette, M.-L., Leclercq, M., Vittrant, B., Frontiers in Genetics, 2020, 10.3389/fgene.2020.550894
Identification of the most important features of knee osteoarthritis structural progressors using machine learning methods, Martel-Pelletier, J., Droit, A., Abram, F., Pelletier, J.-P., Labbe, A., Leclercq, M., Jamshidi, A., Therapeutic Advances in Musculoskeletal Disease, 2020, 10.1177/1759720X20933468
Effect of an isoenergetic traditional mediterranean diet on the high-density lipoprotein proteome in men with the metabolic syndrome, Lamarche, B., Droit, A., Bourassa, S., Nehmé, B., Desroches, S., Couture, P., Richard, C., Journal of Nutrigenetics and Nutrigenomics, 2014, 10.1159/000363137
VEXOR: An integrative environment for prioritization of functional variants in fine-mapping analysis, Droit, A., Simard, J., Kraft, P., Easton, D., Allen, J., Soucy, P., Beauparlant, C.J., Lemaçon, A., Bioinformatics, 2017, 10.1093/bioinformatics/btw826
Extensive and Accurate Benchmarking of DIA Acquisition Methods and Software Tools Using a Complex Proteomic Standard, Arnaud Droit, Mickaël Leclercq, Loïc Mangnier, Charles Joly-Beauparlant, Florence Roux-Dalvai, Clarisse Gotti, Journal of Proteome Research, 2021, 10.1021/acs.jproteome.1c00490
The Ovulatory Signal Precipitates LRH-1 Transcriptional Switching Mediated by Differential Chromatin Accessibility, Gévry, N., Murphy, B.D., Schoonjans, K., Droit, A., Bertolin, K., Beauparlant, C.J., Beaulieu, É., Bellefleur, A.-M., Bianco, S., Cell Reports, 2019, 10.1016/j.celrep.2019.07.088
Adipose Tissue Transcriptome Is Related to Pollutant Exposure in Polar Bear Mother-Cub Pairs from Svalbard, Norway, Routti, H., Bailey, J.L., Droit, A., Gagné, D., Dalvai, M., Bodein, A., Joly Beauparlant, C., Aars, J., Herst, P.M., Environmental Science and Technology, 2020, 10.1021/acs.est.0c01920
The Absence of HIF-1α Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis, Silvestre, R., Estaquier, J., Castro, A.G., Carvalho, A., Cunha, C., Rodrigues, F., Saha, B., Bodhale, N., Sparwasser, T., Berod, L., Droit, A., Beauparlant, C.-J., Gonçalves, L.G., Dinis-Oliveira, R.J., Torrado, E., Barbosa, A.M., Kluck, G.E.G., Moreira, D., Ferreira, C., Mesquita, I., Cell Reports, 2020, 10.1016/j.celrep.2020.02.098
Hedgehog signaling pathway regulates gene expression profile of epididymal principal cells through the primary cilium, Belleannée, C., Cyr, D.G., Droit, A., Joly-Beauparlant, C., Soulet, D., Calvo, E., Bernet, A., Girardet, L., FASEB Journal, 2020, 10.1096/fj.202000328R
Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer, Long, J., Cai, Q., Easton, D.F., Antoniou, A.C., Dunning, A.M., Chenevix-Trench, G., Simard, J., Pharoah, P.D.P., Hall, P., Kristensen, V.N., Seynaeve, C., Martens, J.W.M., Hooning, M.J., Cheng, C.-Y., Floris, G., Zheng, Y., Zamora, P.M., Har Yip, C., Wu, A.H., Winqvist, R., Wen, W., Tseng, C.-C., Truong, T., Tomlinson, I., Tollenaar, R.A.E.M., Toland, A.E., Thienpont, B., Hwang Teo, S., Swerdlow, A., Southey, M.C., Shrubsole, M.J., Hou, M.-F., Shen, C.-Y., Schmutzler, R.K., Schmidt, M.K., Sawyer, E.J., Sangrajrang, S., Rudolph, A., Choudary Putti, T., Peterlongo, P., van den Ouweland, A.M.W., Orr, N., Olson, J.E., Børresen-Dale, A.-L., Nord, S., Nevanlinna, H., Neuhausen, S.L., Muir, K., Meindl, A., McLean, C., Matsuo, K., Marme, F., Margolin, S., Le Marchand, L., Manoukian, S., Mannermaa, A., Lubinski, J., Lophatananon, A., Lindblom, A., Li, J., Lambrechts, D., Kosma, V.-M., Knight, J.A., Khan, S., Kang, D., Kabisch, M., Torres, D., Johnson, N., Jakubowska, A., Ito, H., Hsiung, C.-N., Hopper, J.L., Hollestelle, A., Miao, H., Hartman, M., Hamann, U., Haiman, C.A., Guenel, P., Grip, M., Giles, G.G., García-Closas, M., Gaborieau, V., Fostira, F., Flyger, H., Fletcher, O., Fasching, P.A., Dork, T., Droit, A., Devilee, P., Darabi, H., Czene, K., Cross, S.S., Cox, A., Couch, F.J., Choi, J.-Y., Chang-Claude, J., Canisius, S., Cai, H., Burwinkel, B., Brüning, T., Broeks, A., Brinton, L., Brenner, H., Brauch, H., Bojesen, S.E., Bogdanova, N.V., Blot, W., Beeghly-Fadiel, A., Benitez, J., Guo, X., Zhao, Z., Beckmann, M.W., Arndt, V., Anton-Culver, H., Andrulis, I.L., Kar, S., Beesley, J., Shu, X.-O., Milne, R.L., Lush, M., Dennis, J., Wang, Q., Bolla, M.K., Ghoussaini, M., Michailidou, K., Zheng, W., Zhang, Y., Shi, J., International Journal of Cancer, 2016, 10.1002/ijc.30150
Statistical and machine-learning analyses in nutritional genomics studies, Rudkowska, I., Bilodeau, J.-F., Droit, A., Leclercq, M., Khorraminezhad, L., Nutrients, 2020, 10.3390/nu12103140
The expanding role of poly(ADP-ribose) metabolism: Current challenges and new perspectives, Poirier, G.G., Droit, A., Hendzel, M.J., Gagné, J.-P., Current Opinion in Cell Biology, 2006, 10.1016/j.ceb.2006.02.013
Proteomic Analysis of Maternal Urine for the Early Detection of Preeclampsia and Fetal Growth Restriction, Arnaud Droit, Paul Guerby, Geneviève Laforest, Clarisse Gotti, Jean-Claude Forest, Yves Giguère, Marie Pier Scott-Boyer, Florence Roux-Dalvai, Alexandre Fillion, Emmanuel Bujold, Journal of Clinical Medicine, 2021, 10.3390/jcm10204679
Human Proteinpedia enables sharing of human protein data [4], Pandey, A., Zurbig, P., Zhu, Y., Zhou, M., Zhong, J., Yates, J.R., Xu, T., Wu, B., Wiemann, S., Wang, X., Wait, R., Vihinen, M., Vidal-Taboada, J.-M., Veenstra, T.D., Vasilescu, J., Vandekerckhove, J., Uhlen, M., Trinidad, J.C., Thongboonkerd, V., Takatalo, M., Superti-Furga, G., Sullivan, M., Sugano, S., States, D.J., Smith, R.D., Smith, J.C., Michael Siu, K.W., Sirdeshmukh, R., Simpson, R.J., Shivakumar, K., Shetty, V., Sheng, S.J., Shankari, K., Seshi, B., Sayd, T., Sanchez, J.-C., Salonen, J., Ronnholm, R.H., Rick, J., Rice, R.H., Ramachandra, Y.L., Ramachandran, P., Rahiman, B.A., Purvine, S.O., Prasad, T.S.K., Poirier, G.G., Petricoin, E.F., Periaswamy, B., Pepperkok, R., Pennington, K., Paik, Y.-K., Oyama, M., Omenn, G.S., Oliva, R., Ohara, O., Neubert, T.A., Navarro, J.D., Nalli, A., Muddiman, D.C., Morzel, M., Moritz, R., Morgan, J.D., Moran, M.F., Molina, H., Mohmood, R., Mohan, S.S., Mischak, H., Miller, C.A., Menon, R., Mehrle, A., McRedmond, J., McComb, M., Martinez-Heredia, J., Martens, L., Mann, M., Loo, J.A., Löbke, C., Lim, M.S., Levander, F., Lescuyer, P., Lehvaslaiho, M., Lefevre, M., Lee, Y.-J., Lee, H.-J., Kwon, M.-S., Kuster, B., Körner, R., Korf, U., Kikuno, R.F., Kheterpal, I., Kandasamy, K., Jung, P., Jensen, P.H., Jensen, O.N., James, P., Ibarrola, N., Hruban, R.H., Horn, D.M., Hofmann, O., Hochstrasser, D.F., Hjernø, K., Hide, W., Hermeking, H., Helsens, K., Hebbar, P., He, F., Hays, F., Hart, G., Harsha, H.C., Hancock, W.S., Hanash, S.M., Gromov, P., Goel, R., Gnad, F., Gimble, J.M., Gevaert, K., Gelfi, C., Gagné, P., Figeys, D., Fenselau, C., Fang, X., Falkner, J., Faca, V., Eyk, J.V., Ewing, R.M., Elenitoba-Johnson, K., Dunn, M.J., Droit, A., Drewes, G., Dransfield, E., Deutsch, E.W., DeSouza, L.V., De Marzo, A.M., DeLany, J.P., Crockett, D., Cotter, R.J., Costello, C.E., Cole, P.A., Chu, F., Chaerkady, R., Celis, J.E., Cardasis, H.L., Cantin, G.T., Cagney, G., Bustelo, X.R., Burlingame, A.S., Brahmachari, S.K., Bose, R., Blagoev, B., Björling, E., Bennett, K.L., Bantscheff, M., Balgley, B.M., Bader, J.S., Andrews, P.C., Amanchy, R., Alexandre, H., Ahn, N.G., Ahmed, M., Mathivanan, S., Nature Biotechnology, 2008, 10.1038/nbt0208-164
RT-PSM, a real-time program for peptide-spectrum matching with statistical significance, Poirier, G.G., Droit, A., Gagné, P., Wu, F.-X., Rapid Communications in Mass Spectrometry, 2006, 10.1002/rcm.2435
Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus, Zheng, W., Easton, D.F., Antoniou, A.C., Couch, F.J., Simard, J., Dunning, A.M., Chenevix-Trench, G., Hall, P., Pharoah, P.D.P., Yu, J.-C., Yannoukakos, D., Wu, A.H., Wong, T.Y., Winqvist, R., Whittemore, A.S., Weitzel, J.N., Wang-Gohrke, S., Vijai, J., ven den Berg, D., van Rensburg, E.J., van den Ouweland, A.M.W., Turnbull, C., Tung, N., Toland, A.E., Tischkowitz, M., Tihomirova, L., Thomassen, M., Teulé, A., Tessier, D.C., Terry, M.B., Teo, S.H., Teixeira, M.R., Tchatchou, S., Szabo, C.I., Swerdlow, A., Steinemann, D., Southey, M., Soucy, P., Slager, S., Singer, C.F., Sigurdson, A., Shu, X.-O., Shrubsole, M.J., Shen, C.-Y., Seynaeve, C., Schürmann, P., Schoemaker, M.J., Schmutzler, R.K., Schmidt, M.K., Sawyer, E.J., Sangrajrang, S., Salani, R., Rudolph, A., Rhiem, K., Rennert, G., Rashid, M.U., Ramus, S.J., Rahman, N., Radice, P., Presneau, N., Phelan, C.M., Pfeiler, G., Peto, J., Peterlongo, P., Peissel, B., Peeters, S., Paulsson-Karlsson, Y., Park-Simon, T.-W., Papi, L., Osorio, A., Olswold, C., Olopade, O.I., Olah, E., Offit, K., Nussbaum, R.L., Nord, S., Newcomb, P.A., Nevanlinna, H., Neuhausen, S.L., Nathanson, K.L., Mulligan, A.M., Muir, K., Montagna, M., Menegaux, F., Meindl, A., McGuffog, L., Matsuo, K., Marme, F., Margolin, S., Manoukian, S., Mannermaa, A., Mai, P.L., Lubinski, J., Lophatananon, A., Lindblom, A., Liljegren, A., Li, J., Lester, J., Lee, M.H., Lee, C.N., Le Marchand, L., Lazaro, C., Lambrechts, D., Laitman, Y., Kwong, A., Kraft, P., Konstantopoulou, I., Knight, J.A., Khusnutdinova, E., Khan, S., Kerin, M.J., Kauppila, S., Karlan, B.Y., Kang, D., Kabisch, M., Jones, M., Joly Beauparlant, C., John, E.M., Jensen, U.B., Jaworska-Bieniek, K., Janavicius, R., Jakubowska, A., Ito, H., Isaacs, C., Imyanitov, E.N., Hunter, D.J., Hulick, P.J., Hollestelle, A., Hillemanns, P., Hendricks, C.B., Verhoef, S., Hogervorst, F.B.L., Healey, S., Hassan, N., Hartman, M., Hartikainen, J.M., Hart, S., Hansen, T.V.O., Hamann, U., Hallberg, E., Haiman, C.A., Haeberle, L., Guénel, P., Greene, M.H., González-Neira, A., Goldgar, D.E., Godwin, A.K., Giles, G.G., Stoppa-Lyonnet, D., Mazoyer, S., Lesueur, F., Damiola, F., Gehrig, A., García-Closas, M., Garber, J., Gao, Y.-T., Gambino, G., Friedman, E., Friedlander, M., Flyger, H., Figueroa, J., Fasching, P.A., Lalloo, F., Frost, D., Ellis, S., Ejlertsen, B., Einbeigi, Z., Eilber, U., Egan, K., Dworniczak, B., Dwek, M., Dumont, M., dos-Santos-Silva, I., Dörk, T., Dorfling, C.M., Doody, M., Domchek, S.M., Diez, O., Devilee, P., De Leeneer, K., de la Hoya, M., Daly, M.B., Czene, K., Cross, S.S., Cox, A., Clarke, C., Claes, K.B.M., Choi, J.-Y., Chang-Claude, J., Carpenter, J., Campbell, I., Caldes, T., Cai, Q., Buys, S.S., Burwinkel, B., Brüning, T., Broeks, A., Brenner, H., Brennan, P., Brauch, H., Brand, J.S., Borresen-Dale, A.-L., Bonanni, B., Bojesen, S.E., Bogdanova, N.V., Blot, W.J., Blomqvist, C., Bermisheva, M., Benitez, J., Beeghly-Fadiel, A., Baynes, C., Barrowdale, D., Bacot, F., Arver, B., Arun, B.K., Arndt, V., Arason, A., Antonenkova, N.N., Anton-Culver, H., Andrulis, I.L., Aittomäki, K., Ahmed, S., Agata, S., Dennis, J., Wang, Q., Bolla, M.K., Milne, R.L., Hopper, J.L., Freeman, A., Kar, S., Ghoussaini, M., Michailidou, K., Droit, A., Kuchenbaecker, K.B., Long, J., Guo, X., Zeng, C., Breast Cancer Research, 2016, 10.1186/s13058-016-0718-0
Proteomic dataset for altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells, Bachvarov, D., Bertozzi, C.R., Droit, A., Bourassa, S., Fournier, F., Woo, C.M., Roux-Dalvai, F., Sheta, R., Data in Brief, 2016, 10.1016/j.dib.2016.05.060
DIA proteomics data from a UPS1-spiked E.coli protein mixture processed with six software tools, Arnaud Droit, Mickaël Leclercq, Loïc Mangnier, Charles Joly-Beauparlant, Florence Roux-Dalvai, Clarisse Gotti, Data in Brief, 2022, 10.1016/j.dib.2022.107829
Implementation and Evaluation of a Wiki Involving Multiple Stakeholders Including Patients in the Promotion of Best Practices in Trauma Care: The WikiTrauma, , JMIR Research Protocols, 2015, 10.2196/resprot.4024
Interpretation of network-based integration from multi-omics longitudinal data, Arnaud Droit, Kim-Anh Lê Cao, Olivier Perin, Marie-Pier Scott-Boyer, Antoine Bodein, Nucleic Acids Research, 2022, 10.1093/nar/gkab1200
Bio2RDF release 3: A larger connected network of linked data for the life sciences, Droit, A., Belleau, F., Emonet, V., Ansell, P., Cruz-Toledo, J., Callahan, A., Dumontier, M., CEUR Workshop Proceedings, 2014
Long-term Memory Testing in Children With Typical Development and Neurodevelopmental Disorders: Remote Web-based Image Task Feasibility Study (Preprint), Francois V Bolduc, Jacqueline Pei, Sandra A Wiebe, Arnaud Droit, Savannah Weber, Mickael Leclercq, Kerri Hope Whitlock, Cory Scott Rosenfelt, Truong An Bui, 2022, 10.2196/preprints.39720
Vitamin C Differentially Impacts the Serum Proteome Profile in Female and Male Mice, Michel Lebel, Arnaud Droit, Clarisse Gotti, Sylvie Bourassa, Lucie Aumailley, Journal of Proteome Research, 2021, 10.1021/acs.jproteome.1c00542
A Generic Multivariate Framework for the Integration of Microbiome Longitudinal Studies With Other Data Types, Lê Cao, K.-A., Droit, A., Chapleur, O., Bodein, A., Frontiers in Genetics, 2019, 10.3389/fgene.2019.00963
Analysis of the translatome in solid tumors using polyribosome profiling/RNA-Seq, Rachid Mazroui, Paul Toren, Edouard W. Khandjian, Arnaud Droit, Valerie Grenier St-Sauveur, Pauline Adjibade, Journal of Biological Methods, 2016, 10.14440/jbm.2016.151
Erratum: Inferring and modeling inheritance of differentially methylated changes across multiple generations (Nucleic acids research (2018) 46 14 (e85)), Droit, A., Bailey, J., Kimmins, S., Dalvai, M., Lambrot, R., Scott-Boyer, M.-P., Deschênes, A., Belleau, P., Nucleic acids research, 2018, 10.1093/nar/gky477
Skeletal muscle proteomic signature and metabolic impairment in pulmonary hypertension, Provencher, S., Bonnet, S., Droit, A., Nehmé, B., Tremblay, È., Bourassa, S., Pflieger, A., Breuils-Bonnet, S., Fournier, F., Potus, F., Malenfant, S., Journal of Molecular Medicine, 2015, 10.1007/s00109-014-1244-0
Quantitative site-specific ADP-ribosylation profiling of DNA-dependent PARPs, Poirier, G.G., Droit, A., Figeys, D., Ning, Z., Foster, L.J., Moon, K.-M., Pascal, J.M., Riccio, A.A., Langelier, M.-F., Bourassa, S., Defoy, D., Ethier, C., Gagné, J.-P., DNA Repair, 2015, 10.1016/j.dnarep.2015.02.004
Personalized Risk Assessment for Prevention and Early Detection of Breast Cancer: Integration and Implementation (PERSPECTIVE I&I), Jacques Simard, Anna Chiarelli, Michael Wolfson, Meghan Walker, Sean Tavtigian, Tracy Stockley, Rita Schmutzler, Nora Pashayan, Jean-Sébastien Paquette, Nicole Mittmann, Jean-Yves Masson, Aisha Lofters, Bartha Knoppers, Eric Hahnen, Yann Joly, David Goldgar, Samantha Fienberg, Laurence Eloy, Andrea Eisen, Douglas Easton, Arnaud Droit, Michel Dorval, Peter Devilee, Philippe Després, Jocelyne Chiquette, Antonis Antoniou, Irene Andrulis, Hermann Nabi, Jennifer Brooks, Journal of Personalized Medicine, 2021, 10.3390/jpm11060511
A Machine Learning Approach to Identify Key Residues Involved in Protein–Protein Interactions Exemplified with SARS-CoV-2 Variants, Arnaud Droit, Gautier Moroy, Marie-Pier Scott-Boyer, Julien Prunier, Mickael Leclercq, Léopold Quitté, International Journal of Molecular Sciences, 2024, 10.3390/ijms25126535
Interpretation of network-based integration from multi-omics longitudinal data, , 2020, 10.1101/2020.11.02.365593
Transcriptomic profile of the subiculum-projecting VIP GABAergic neurons in the mouse CA1 hippocampus, Topolnik, L., Droit, A., Vallée, M., Francavilla, R., Muñoz-Pino, E., Luo, X., Brain Structure and Function, 2019, 10.1007/s00429-019-01883-z
A metabolic labeling approach for glycoproteomic analysis reveals altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells, Bachvarov, D., Bertozzi, C.R., Droit, A., Bourassa, S., Fournier, F., Roux-Dalvai, F., Woo, C.M., Sheta, R., Journal of Proteomics, 2016, 10.1016/j.jprot.2016.04.009
Integration of high-resolution methylome and transcriptome analyses to dissect epigenomic changes in childhood acute lymphoblastic leukemia, Pastinen, T., Sinnett, D., Droit, A., Chen, S.-H., Healy, J., Richer, C., Saillour, V., Spinella, J.-F., Vidal, R., Ge, B., Busche, S., Cancer Research, 2013, 10.1158/0008-5472.CAN-12-4367
UGT2B17 modifies drug response in chronic lymphocytic leukaemia, Guillemette, C., Lévesque, E., Staber, P.B., Jäger, U., Droit, A., Joly-Beauparlant, C., Hubmann, R., Demirtas, D., Schnabl, S., Shehata, M., Le, T., Turcotte, V., Labriet, A., Villeneuve, L., Caron, P., Bat, V., Vaillancourt, J., Tremblay, S., Vanura, K., Rouleau, M., Allain, E.P., British Journal of Cancer, 2020, 10.1038/s41416-020-0887-6
PARPs database: A LIMS systems for protein-protein interaction data mining or laboratory information management system, Poirier, G.G., Bourgais, D., Picard-Cloutier, A., Ethier, C., Rouleau, M., Hunter, J.M., Droit, A., BMC Bioinformatics, 2007, 10.1186/1471-2105-8-483
Evaluation of iTRAQ and SWATH-MS for the quantification of proteins associated with insulin resistance in human duodenal biopsy samples, Droit, A., Couture, P., Lamarche, B., Lemelin, V., Tremblay, A., Kelly, I., Nehmé, B., Fournier, F., Bourassa, S., PLoS ONE, 2015, 10.1371/journal.pone.0125934
Alternative promoters control UGT2B17-dependent androgen catabolism in prostate cancer and its influence on progression, Guillemette, C., Lacombe, L., Fradet, Y., Simonyan, D., Audet-Walsh, E., Droit, A., Leclercq, M., Villeneuve, L., Caron, P., Turcotte, V., Rouleau, M., Brisson, H., Melo-Garcia, L., Allain, É.P., Hovington, H., Labriet, A., Lévesque, E., British Journal of Cancer, 2020, 10.1038/s41416-020-0749-2
Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs), Dunning, A.M., Chenevix-Trench, G., French, J.D., Simard, J., Edwards, S.L., Hall, P., Pharoah, P.D.P., Zheng, W., Yip, C.H., Wu, P.-E., Wu, A.H., Winqvist, R., Vincent, D., Vachon, C.M., Truong, T., Torres, D., Tomlinson, I., Tessier, D.C., Teo, S.H., Swerdlow, A., Surowy, H., Stram, D.O., Southey, M.C., Shu, X.-O., Shen, C.-Y., Shah, M., Seynaeve, C., Schmutzler, R.K., Schmidt, M.K., Sawyer, E.J., Sangrajrang, S., Rudolph, A., Pylkäs, K., Pita, G., Peterlongo, P., Orr, N., Olswold, C., Nevanlinna, H., Neuhausen, S.L., Muir, K., Milne, R.L., Meindl, A., McKay, J., Mayes, R., Matsuo, K., Margolin, S., Manoukian, S., Mannermaa, A., Lubinski, J., Lophatananon, A., Lindblom, A., Lee, S.C., Le Marchand, L., Lambrechts, D., Kristensen, V., Kriege, M., Kosma, V.-M., Khan, S., Kang, D., Johnson, N., Jakubowska, A., Ito, H., Hopper, J.L., Hollestelle, A., Hartman, M., Hamann, U., Hallberg, E., Haiman, C.A., Guénel, P., González-Neira, A., Goldberg, M.S., Giles, G.G., García-Closas, M., Galle, E., Flyger, H., Fletcher, O., Figueroa, J., Fasching, P.A., Easton, D.F., Dörk, T., Devilee, P., Czene, K., Cross, S.S., Cox, A., Couch, F.J., Conroy, D.M., Choi, J.-Y., Chang-Claude, J., Burwinkel, B., Brüning, T., Broeks, A., Brenner, H., Brauch, H., Bojesen, S.E., Bogdanova, N.V., Benitez, J., Beckmann, M.W., Arndt, V., Anton-Culver, H., Andrulis, I.L., Alonso, M.R., Dennis, J., Wang, Q., Bolla, M.K., Wahl, H.F., Ghoussaini, M., Michailidou, K., Soucy, P., Marjaneh, M.M., Nord, S., Kar, S., Droit, A., Beesley, J., Darabi, H., Scientific Reports, 2016, 10.1038/srep32512
Proteomic and genomic analyses of antimony resistant Leishmania infantum mutant, Ouellette, M., Droit, A., Poirier, G.G., Légaré, D., Leprohon, P., Bourassa, S., Brotherton, M.-C., PLoS ONE, 2013, 10.1371/journal.pone.0081899
Quantitative profiling of the UGT transcriptome in human drug-metabolizing tissues, Guillemette, C., Droit, A., Gilbert, I., Villeneuve, L., Guauque-Olarte, S., Rouleau, M., Tourancheau, A., Pharmacogenomics Journal, 2018, 10.1038/tpj.2017.5
Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3, Simard, J., Antoniou, A.C., Easton, D.F., Nord, S., Couch, F.J., Offit, K., Chenevix-Trench, G., Rebbeck, T., Wijnen, J.T., Wappenschmidt, B., Varon-Mateeva, R., van Rensburg, E.J., van Engelen, K., van der Luijt, R.B., van den Ouweland, A.M.W., Tung, N., Toland, A.E., Tognazzo, S., Tischkowitz, M., Tihomirova, L., Thomassen, M., Terry, M.B., Teo, S.-H., Teulé, A., Teixeira, M.R., Tea, M.-K., Tan, Y., Sutter, C., Sukiennicki, G., Stoppa-Lyonnet, D., Stadler, Z., Spurdle, A.B., Southey, M., Sønderstrup, I.M.H., Sokolowska, J., Snape, K., Slavin, T.P., Singer, C.F., Shah, P.D., Sevenet, N., Schmutzler, R.K., Rookus, M.A., Rodriguez, G.C., Robson, M., Richardson, A., Rennert, G., Rappaport-Fuerhauser, C., Rantala, J., Radice, P., Phelan, C.M., Peterlongo, P., Segura, P.P., Peissel, B., Pedersen, I.S., Park, S.K., Papi, L., Osorio, A., Oosterwijk, J.C., Ong, K.-R., Olopade, O.I., Olah, E., Nussbaum, R.L., Nevanlinna, H., Neuhausen, S.L., Nathanson, K.L., Mulligan, A.M., Montagna, M., Miller, A., Meindl, A., Meijers-Heijboer, H.E.J., McGuffog, L., Mazoyer, S., Mariani, M., Manoukian, S., Loud, J.T., Loman, N., Liljegren, A., Lesueur, F., Lester, J., Leslie, G., Lazaro, C., Laurent, M., Laitman, Y., Kriege, M., Kirk, J., Kets, C.M., Karlan, B.Y., Kaczmarek, K., Just, W., Joseph, V., John, E.M., Jensen, U.B., Janavicius, R., James, P., Jakubowska, A., Izatt, L., Isaacs, C., Imyanitov, E.N., Hulick, P.J., Hogervorst, F.B.L., Hart, S., Hays, J.L., Hansen, T.V.O., Hamann, U., Hahnen, E., Gronwald, J., Greene, M.H., Goldgar, D.E., Godwin, A.K., Glendon, G., Gerdes, A.-M., Gayther, S.A., Garber, J., Ganz, P.A., Ganschow, P., Frost, D., Friedman, E., Fountzilas, G., Foulkes, W.D., Fostira, F., Foretova, L., Feliubadalo, L., Gareth Evans, D., Engel, C., Ejlertsen, B., Einbeigi, Z., Eeles, R., Eccles, D., Dorfling, C.M., Domchek, S.M., Dolcetti, R., Ding, Y.C., Diez, O., De Leeneer, K., De la Hoya, M., Davidson, R., Damiola, F., Daly, M.B., Claes, K.B.M., Chung, W.K., Chiquette, J., Caligo, M.A., Buys, S.S., Buecher, B., Brewer, C., Bradbury, A.R., Bonanni, B., Bonadona, V., Bobolis, K., Blok, M.J., Berthet, P., Benitez, J., Barrowdale, D., Barjhoux, L., Bane, A., Azzollini, J., Arun, B.K., Arnold, N., Arason, A., Andrulis, I.L., Aittomäki, K., Adlard, J., Lemaçon, A., Droit, A., Pastinen, T., Kuchenbaeker, K.B., Soucy, P., Hamdi, Y., Breast Cancer Research and Treatment, 2017, 10.1007/s10549-016-4018-2

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Contribution à l'enseignement aux cycles supérieurs

Étudiant(e)s dirigé(e)s*

Depuis 2009

Virgile Raufaste-Cazavieille - Doctorat - En cours
Milan Picard - Doctorat - En cours
Christophe Tav - Doctorat - En cours
Elloise Coyle - Doctorat - En cours
Mathieu Arru - Doctorat - En cours
Sophiane Bouirdene - Doctorat - En cours
Kehau-Lani Feral - Doctorat - En cours
Thomas Jeanne - Doctorat - En cours
Guillaume Frederic Jean Lemaire - Doctorat - En cours
Jordan-Adam Ortona - Maîtrise avec mémoire - En cours
Emilie Dehon - Doctorat - En cours
Léopold Quitté - Doctorat - En cours
Elsa Claude - Doctorat - En cours
Mona Patoughi - Doctorat - En cours
Steven Boutrais - Doctorat - En cours
Damien Carrasquet - Doctorat - En cours
Olivia Gavard - Doctorat - 2016/01
Alan Tourancheau - Doctorat - 2016/01
Jean-Sébastien Milanese - Maîtrise avec mémoire - 2017/09
Audrey Lemaçon - Doctorat - 2019/01
Alexandra Carrier - Maîtrise avec mémoire - 2019/01
Benjamin Vittrant - Doctorat - 2021/01
Antoine Bodein - Doctorat - 2021/05
Louis Cossus - Doctorat - 2021/05
Roxanne Sergerie - Maîtrise avec mémoire - 2022/01
Régis Ongaro-Carcy - Doctorat - 2022/05
Andréanne Gagné - Doctorat - 2022/09
Loïc Mangnier - Doctorat - 2022/09
Khawla Seddiki - Doctorat - 2023/05
Antoine Lacombe - Maîtrise avec mémoire - 2023/09
Paul-Emmanuel Edeline - Doctorat - 2024/05
Louis Ohl - Doctorat - 2024/05

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Médecine moléculaire

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*Les supervisions d’étudiant(e)s de 1er cycle en stage de recherche et de résident(e)s aux études médicales postdoctorales seront répertoriées ultérieurement.

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