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Claudia Gagnon

Médecin clinicienne enseignante agrégée

Claudia Gagnon
claudia.gagnon@fmed.ulaval.ca
Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec
Centre de recherche du CHU de Québec - Université Laval
Centre de recherche de l'IUCPQ
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Contribution à la recherche

Axe de recherche de l'Université Laval :

Santé et bien-être durables

Thématiques de recherche de la Faculté de médecine :

Santé cardiovasculaire, respiratoire et métabolisme
Santé des populations et pratiques optimales en santé

Domaines et intérêts de recherche du (de la) professeur(e) :

Appareil locomoteur et arthrite
  • Ostéoporose
Nutrition et métabolisme
  • Diabète
  • Obésité
  • Désordres endocriniens
  • Nutrition

Projets de recherche

  • Santé osseuse et musculaire après une gastrectomie en manchon chez des hommes, des femmes préménopausées et des femmes ménopausées - CHU de Québec – Université Laval – CHUL - Développement de la recherche (FC), chercheur principal - 2023-03-01 au 2028-07-01
  • Bone and Muscle Health Following Sleeve Gastrectomy in Men, Premenopausal and Postmenopausal Women - Instituts de recherche en santé du Canada - Subvention Projet, chercheur principal - 2022-04-01 au 2027-03-31
  • Impact of glycemic control on skeletal outcomes in adults with type 1 diabetes - Diabète Canada - Subvention de fonctionnement : Mettre fin au diabète prix 2022, chercheur principal - 2022-12-01 au 2025-11-30
  • Multifaceted Intervention using Telehealth to Reduce the risk of Falls and Fractures in Older Men (MisterFit study): a Pilot Study - Instituts de recherche en santé du Canada, University of Waterloo, co-chercheur - 2021-10-01 au 2025-09-30
  • Identifying low bone turnover disease in chronic kidney disease in order to guide anti-fracture therapy - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2020-10-01 au 2025-09-30
  • Impact de l'obésité, du diabète et de la chirurgie bariatrique sur la santé osseuse. - Fonds de recherche du Québec - Santé - Chercheurs-boursiers cliniciens - Juniors 1 et 2, Seniors, chercheur principal - 2023-07-01 au 2025-06-30
  • Chaire de recherche diabète et maladies endocriniennes - Fondation du CHU de Québec, chercheur principal - 2023-04-27 au 2025-04-26
  • La santé osseuse après une chirurgie bariatrique chez des patients ayant un diabète de type 2 - suivi 3 ans post chirurgie - CHU de Québec – Université Laval – CHUL - Développement de la recherche (FC), chercheur principal - 2022-01-01 au 2024-12-31
  • Effet de contrôle glycémique sur la progression de la stéatose hépatique au sein du REGISTRE-NASH du CHU de Québec-Université Laval - CHU de Québec – Université Laval – CHUL - Subvention en recherche clinique (PCRE), co-chercheur - 2024-01-23 au 2024-12-31
  • A new focus on protein and the gut microbiota to explain health benefits of dairy foods - Les producteurs laitiers du Canada, co-chercheur - 2022-01-01 au 2024-12-31
  • Impact of Glycemic Variability on Cognitive Impairment, Disordered Eating Behaviors and Self-Management Skills in Patients with Type 1 Diabetes - Diabète Canada - Research Competition, co-chercheur - 2021-12-01 au 2024-11-30
  • Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 1.3 - Instituts de recherche en santé du Canada - Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche, co-chercheur - 2019-11-01 au 2024-10-31
  • Prix Jeune Chercheur 2022 de la Société canadienne d'endocrinologie et métabolisme - Canadian Society of Endocrinology and Metabolism, chercheur principal - 2022-09-14 au 2024-09-13
  • Institut sur la nutrition et les aliments fonctionnels (INAF) - Institut national de recherche scientifique (INRS), Fonds de recherche du Québec - Nature et technologies, Université Laval - Fonds internes, Université McGill, Université du Québec à Rimouski, Université de Sherbrooke - Regroupements stratégiques NT, co-chercheur - 2017-04-01 au 2024-03-31
  • Bone health after bariatric surgery in patient with type 2 diabetes - Association canadienne du diabète - Compétition de recherche 2017, chercheur principal - 2017-07-01 au 2022-12-31
  • Covid-19 effects on ARTErial StIffness and vascular AgiNg (CARTESIAN) study- Canada - Instituts de recherche en santé du Canada - Subvention de fonctionnement : Possibilité de financement sur les nouveaux besoins prioritaires en recherche sur la COVID-19, co-chercheur - 2021-06-01 au 2022-05-31
  • Traiter l’os pour prévenir l’hypertension et les maladies cardiovasculaires chez les femmes ménopausées. - Alliance santé Québec (AsQ), co-chercheur - 2021-05-01 au 2022-04-30
  • Translational approach to establish the cardiometabolic health effects and mechanisms of action of fish nutrients: from animal models to obese insulin-resistant subjects - Cooke Aquaculture, Instituts de recherche en santé du Canada - Subventions de recherche programmatique sur l’alimentation et la santé, co-chercheur - 2013-06-01 au 2021-03-31

Publications

  • Longitudinal Assessment of Vitamin D Status across Trimesters of Pregnancy, Morisset, A.-S., Weiler, H.A., Gagnon, C., Lemieux, S., Plante, A.-S., Bielecki, A., Savard, C., Journal of Nutrition, 2021, 10.1093/jn/nxab060
  • Cholecalciferol Supplementation Does Not Prevent the Development of Metabolic Syndrome or Enhance the Beneficial Effects of Omega-3 Fatty Acids in Obese Mice, Marette, A., Bazinet, L., Gagnon, C., Levy, E., Delvin, E., Jacques, H., Vohl, M.-C., Richard, D., Varin, T., St-Pierre, P., Pilon, G., Mitchell, P.L., Valle, M., Journal of Nutrition, 2021, 10.1093/jn/nxab002
  • Effects of Biliopancreatic Diversion on Bone Turnover Markers and Association with Hormonal Factors in Patients with Severe Obesity, Gagnon, C., Marceau, S., Lebel, S., Biertho, L., Tchernof, A., Michou, L., Mac-Way, F., Carpentier, A.C., Carreau, A.-M., Simonyan, D., Ung, R.-V., Grenier-Larouche, T., Turcotte, A.-F., Obesity Surgery, 2019, 10.1007/s11695-018-3617-x
  • Impact of health professionals' contact frequency on response to a lifestyle intervention with individuals at high risk for diabetes, Langlois, M.-F., Brown, C., Gagnon, C., Baillargeon, J.-P., Bouchard, D.R., Diabetes Research and Clinical Practice, 2012, 10.1016/j.diabres.2011.12.019
  • Prevalence of vitamin D deficiency and its determinants in Australian adults aged 25 years and older: A national, population-based study, Shaw, J.E., Ebeling, P.R., Zimmet, P.Z., Sikaris, K.A., Dunstan, D.W., Magliano, D.J., Lu, Z.X., Gagnon, C., Daly, R.M., Clinical Endocrinology, 2012, 10.1111/j.1365-2265.2011.04320.x
  • Suitability of recommended limits for fasting glucose tests in women with polycystic ovary syndrome, Baillargeon, J.-P., Gagnon, C., CMAJ. Canadian Medical Association Journal, 2007, 10.1503/cmaj.060607
  • Disparities in the timing and measurement methods to assess Vitamin D status during pregnancy: A narrative review, Morisset, A.-S., Gagnon, C., Savard, C., International Journal for Vitamin and Nutrition Research, 2018, 10.1024/0300-9831/a000507
  • Frequent walking, but not total physical activity, is associated with increased fracture incidence: A 5-year follow-up of an Australian population-based prospective study (AusDiab), Daly, R.M., Shaw, J.E., Zimmet, P.Z., Lu, Z.X., Ebeling, P.R., Magliano, D.J., Dunstan, D.W., Gagnon, C., Nikander, R., Journal of Bone and Mineral Research, 2011, 10.1002/jbmr.363
  • Low serum 25-hydroxyvitamin D is associated with increased risk of the development of the metabolic syndrome at five years: Results from a national, population-based prospective study (The Australian Diabetes, Obesity and Lifestyle Study: AusDiab), Daly, R.M., Ebeling, P.R., Sikaris, K., Zimmet, P.Z., Shaw, J.E., Dunstan, D.W., Magliano, D.J., Lu, Z.X., Gagnon, C., Journal of Clinical Endocrinology and Metabolism, 2012, 10.1210/jc.2011-3187
  • Osteoporosis in men: Its pathophysiology and the role of teriparatide in its treatment, Ebeling, P.R., Li, V., Gagnon, C., Clinical Interventions in Aging, 2008
  • Trimester-specific assessment of diet quality in a sample of Canadian pregnant women, Morisset, A.-S., Robitaille, J., Gagnon, C., Provencher, V., Carbonneau, É., Lemieux, S., Savard, C., International Journal of Environmental Research and Public Health, 2019, 10.3390/ijerph16030311
  • Clinical outcomes, predictors, and prevalence of anterior pituitary disorders following traumatic Brain Injury: A systematic Review, Cook, D., Gagnon, C., Bernard, F., Moore, L., Lamontagne, F., Archambault, P.M., Lachance, O., Côté, I., Shemilt, M., Boutin, A., Turgeon, A.F., Lauzier, F., Critical Care Medicine, 2014, 10.1097/CCM.0000000000000046
  • Reproducibility of the 6-minute walk test in obese adults, Langlois, M.-F., Ardilouze, J.-L., Baillargeon, J.-P., Ménard, J., Gagnon, C., Carpentier, A.C., Beriault, K., International Journal of Sports Medicine, 2009, 10.1055/s-0029-1231043
  • Prebiotics in the management of components of the metabolic syndrome, Rudkowska, I., Gagnon, C., Chouinard-Castonguay, S., O'Connor, S., Maturitas, 2017, 10.1016/j.maturitas.2017.07.005
  • Lack of sustained response to teriparatide in a patient with adult hypophosphatasia, Ebeling, P.R., Ng, K.W., Poulton, I.J., Jung, C., McAuley, S.A., Mumm, S., Sims, N.A., Gagnon, C., Journal of Clinical Endocrinology and Metabolism, 2010, 10.1210/jc.2009-1965
  • Impact of a High Intake of Dairy Product on Insulin Sensitivity in Hyperinsulinemic Adults: A Crossover Randomized Controlled Trial, Rudkowska, I., Gagnon, C., Weisnagel, S.J., Julien, P., O'Connor, S., Current Developments in Nutrition, 2019, 10.1093/cdn/nzz083
  • Risk Factors for Recurrent Diabetic Ketoacidosis in Adults With Type 1 Diabetes, Boulet, G., Gagnon, C., Dubé, F., Del Degan, S., Canadian Journal of Diabetes, 2019, 10.1016/j.jcjd.2019.01.008
  • Predictors of success to weight-loss intervention program in individuals at high risk for type 2 diabetes, Baillargeon, J.-P., Brown, C., Gagnon, C., Kamga-Ngandé, C., Langlois, M.-F., Kong, W., Diabetes Research and Clinical Practice, 2010, 10.1016/j.diabres.2010.06.031
  • Zoledronic acid for the treatment of osteoporosis, Ebeling, P.R., Gagnon, C., Medicine Today, 2010
  • Acute effects of single doses of bonito fish peptides and vitamin D on whole blood gene expression levels: A randomized controlled trial, Vohl, M.-C., Marette, A., Gagnon, C., Jacques, H., Guénard, F., International Journal of Molecular Sciences, 2019, 10.3390/ijms20081944
  • Prevalence and predictors of vitamin D insufficiency in women of reproductive age living in northern latitude, Fink, G.D., Desmarais, G., Baillargeon, J.-P., Gagnon, C., European Journal of Endocrinology, 2010, 10.1530/EJE-10-0441
  • Comparison of foot-to-foot and hand-to-foot bioelectrical impedance methods in a population with a wide range of body mass indices, Langlois, M.-F., Carpentier, A.C., Baillargeon, J.-P., Ardilouze, J.-L., Bourbonnais, A., Ménard, J., Gagnon, C., Metabolic Syndrome and Related Disorders, 2010, 10.1089/met.2010.0013
  • Efficacy and safety of oral continuous low-dose versus short-term high-dose vitamin D: A prospective randomised trial conducted in a clinical setting, Ebeling, P.R., Anpalahan, M., Lam, S., Briscoe, R.K., Gagnon, C., Hackman, K.L., Medical Journal of Australia, 2010, 10.5694/j.1326-5377.2010.tb03702.x
  • Salmon peptides limit obesity-associated metabolic disorders by modulating a gut-liver axis in vitamin D-deficient mice, Marette, A., Bazinet, L., Gagnon, C., Jacques, H., Vohl, M.-C., Richard, D., Gill, T., McLeod, R., Rolin, J., Hénault, L., Varin, T., Pilon, G., Mitchell, P.L., Valle, M., Obesity, 2021, 10.1002/oby.23244
  • Association between obesity and risk of fracture, bone mineral density and bone quality in adults: A systematic review and meta-analysis, Gagnon, C., Jean, S., Willie, B.M., Gibbs, J.C., Morin, S.N., O'Connor, S., Turcotte, A.F., PLoS ONE, 2021, 10.1371/journal.pone.0252487
  • Increase in depression symptoms with weight loss: Association with glucose homeostasis and thyroid function, Tremblay, A., Gagnon, C., Arguin, H., Chaput, J.-P., Applied Physiology, Nutrition and Metabolism, 2008, 10.1139/H07-137
  • Increased Dairy Product Intake Alters Serum Metabolite Profiles in Subjects at Risk of Developing Type 2 Diabetes, Rudkowska, I., Bilodeau, J.-F., Droit, A., Gagnon, C., Weisnagel, S.J., Julien, P., Leclercq, M., Greffard, K., O'Connor, S., Molecular Nutrition and Food Research, 2019, 10.1002/mnfr.201900126
  • Associations between serum 25-hydroxyvitamin D, insulin sensitivity, insulin secretion, and β-cell function according to glucose tolerance status, Gagnon, C., Bergeron, J., Lemieux, S., Weisnagel, J., Tardio, V., Morisset, A.-S., Metabolic Syndrome and Related Disorders, 2015, 10.1089/met.2014.0159
  • Effects of combined calcium and vitamin D supplementation on insulin secretion, insulin sensitivity and β-cell function in multi-ethnic vitamin D-deficient adults at risk for type 2 diabetes: A pilot randomized, placebo-controlled trial, Ebeling, P.R., Jean, S., Sikaris, K., Shore-Lorenti, C., Lu, Z.X., Carpentier, A., Daly, R.M., Gagnon, C., PLoS ONE, 2014, 10.1371/journal.pone.0109607
  • A cost-effective moderate-intensity interdisciplinary weight-management programme for individuals with prediabetes, Langlois, M.F., Carpentier, A.C., Baillargeon, J.P., Hivert, M.F., Kamga-Ngande, C.N., Couture, C., Brown, C., Gagnon, C., Diabetes and Metabolism, 2011, 10.1016/j.diabet.2011.01.003
  • Trimester-specific dietary intakes in a sample of French-Canadian pregnant women in comparison with national nutritional guidelines, Morisset, A.-S., Robitaille, J., Gagnon, C., Fontaine-Bisson, B., Weisnagel, S.J., Lemieux, S., Savard, C., Nutrients, 2018, 10.3390/nu10060768
  • Serum 25-hydroxyvitamin D, calcium intake, and risk of type 2 diabetes after 5 years: Results from a national, population-based prospective study (the Australian diabetes, obesity and lifestyle study), Daly, R.M., Ebeling, P.R., Grantham, N., Sikaris, K., Zimmet, P.Z., Shaw, J.E., Dunstan, D.W., Magliano, D.J., Lu, Z.X., Gagnon, C., Diabetes Care, 2011, 10.2337/dc10-2167
  • Bone Marrow Adiposity, Bone Mineral Density and Wnt/β-catenin Pathway Inhibitors Levels in Hemodialysis Patients, Mac-Way, F., Gagnon, C., Samson, F., Ung, R.-V., De Halleux, C., Khelifi, N., Wang, Y.-P., Journal of Bone Metabolism, 2022, 10.11005/jbm.2022.29.2.113
  • Effects of 6-month Vitamin D supplementation on insulin sensitivity and secretion: A randomised, placebo-controlled trial, Gagnon, C., Vohl, M.-C., Marette, A., Bergeron, J., Robitaille, J., Tchernof, A., Poirier, J., Carreau, A.-M., Morisset, A.-S., Julien, A.-S., Caron, A.Z., John Weisnagel, S., Lemieux, P., European Journal of Endocrinology, 2019, 10.1530/EJE-19-0156
  • Dairy product intake modifies gut microbiota composition among hyperinsulinemic individuals, Rudkowska, I., Droit, A., Gagnon, C., Weisnagel, S.J., Julien, P., O’Connor, S., Leclercq, M., Khorraminezhad, L., European Journal of Nutrition, 2021, 10.1007/s00394-020-02226-z
  • Bone Health After Bariatric Surgery, Schafer, A.L., Gagnon, C., JBMR Plus, 2018, 10.1002/jbm4.10048
  • The increase in serum 25-hydroxyvitamin D following weight loss does not contribute to the improvement in insulin sensitivity, insulin secretion and β-cell function, Gagnon, C., Langlois, M.-F., Baillargeon, J.-P., Carpentier, A.C., Brown, C., Morisset, A.-S., Thibault, V., British Journal of Nutrition, 2015, 10.1017/S0007114515001610
  • Prevalence of Vertebral Fractures in Adults With Type 1 Diabetes: DenSiFy Study (Diabetes Spine Fractures), Gagnon, C., Rabasa-Lhoret, R., Morin, S.N., Albert, C., Mac-Way, F., Weisnagel, S.J., Michou, L., Genest, M., Leslie, W.D., Garceau, É., Coll, J.-C., Journal of Clinical Endocrinology and Metabolism, 2022, 10.1210/clinem/dgac031
  • Association between hyperglycaemia and fracture risk in non-diabetic middle-aged and older Australians: A national, population-based prospective study (AusDiab), Daly, R.M., Shaw, J.E., Zimmet, P.Z., Dunstan, D.W., Ebeling, P.R., Magliano, D.J., Gagnon, C., Osteoporosis International, 2010, 10.1007/s00198-009-1164-y
  • Changes in spinal bone density, back muscle size, and visceral adipose tissue and their interaction following a multi-component exercise program in older men: secondary analysis of an 18-month randomized controlled trial, Daly, R.M., Abbott, G., Gagnon, C., Dalla Via, J., Kukuljan, S., Turcotte, A.-F., Osteoporosis International, 2020, 10.1007/s00198-020-05484-z
  • Increased Dairy Product Intake Modifies Plasma Glucose Concentrations and Glycated Hemoglobin: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Rudkowska, I., Gagnon, C., Turcotte, A.-F., O'Connor, S., Advances in Nutrition, 2019, 10.1093/advances/nmy074
  • Bile acids during pregnancy: Trimester variations and associations with glucose homeostasis, Morisset, A.-S., Barbier, O., Carreau, A.-M., Gagnon, C., Weisnagel, S.J., Trottier, J., Gagnon, M., Health Science Reports, 2021, 10.1002/hsr2.243
  • 25-hydroxyvitamin D Levels and chronic kidney disease in the AusDiab (Australian Diabetes, Obesity and Lifestyle) study, Polkinghorne, K.R., Shaw, J.E., Kerr, P.G., Atkins, R.C., Chadban, S.J., Ebeling, P.R., Lu, Z.X., Gagnon, C., Daly, R.M., Magliano, D.J., Damasiewicz, M.J., BMC Nephrology, 2012, 10.1186/1471-2369-13-55
  • Serum 25-hydroxyvitamin D deficiency and the 5-year incidence of CKD, Polkinghorne, K.R., Shaw, J.E., Kerr, P.G., Atkins, R.C., Chadban, S.J., Ebeling, P.R., Sikaris, K.A., Lu, Z.X., Gagnon, C., Daly, R.M., Magliano, D.J., Damasiewicz, M.J., American Journal of Kidney Diseases, 2013, 10.1053/j.ajkd.2013.03.010
  • Association between changes in bioactive osteocalcin and glucose homeostasis after biliopancreatic diversion, Gagnon, C., Ferron, M., Marceau, S., Lebel, S., Biertho, L., Richard, D., Tchernof, A., Mac-Way, F., Carpentier, A.C., Carreau, A.-M., Lacombe, J., Grenier-Larouche, T., Turcotte, A.-F., Endocrine, 2020, 10.1007/s12020-020-02340-2
  • Dietary intakes in pregnant women with previous bariatric surgery, Morisset, A.-S., Tchernof, A., Biertho, L., Marceau, S., Michaud, A., Veillette, J., Gagnon, C., Weisnagel, S.J., Lemieux, S., Savard, C., Plante, A.-S., Carreau, A.-M., Gagnon, G., Eating and Weight Disorders, 2022, 10.1007/s40519-021-01333-y
  • Change in fracture risk and fracture pattern after bariatric surgery: Nested case-control study, Gagnon, C., Michou, L., Biertho, L., Mac-Way, F., Lebel, S., Gamache, P., Jean, S., Rousseau, C., BMJ (Online), 2016, 10.1136/bmj.i3794
  • Vitamin D reduces LPS-induced cytokine release in omental adipose tissue of women but not men, Gagnon, C., Tchernof, A., Marette, A., Bellmann, K., Valle, M., Nadeau, M., Roy, P., Steroids, 2015, 10.1016/j.steroids.2015.08.014
  • Dietary Intakes in Pregnant Women with Previous Bariatric Surgery, Morisset, A.-S., Tchernof, A., Biertho, L., Marceau, S., Michaud, A., Veillette, J., Gagnon, C., Weisnagel, S.J., Lemieux, S., Savard, C., Plante, A.-S., Carreau, A.-M., Gagnon, G., ResearchSquare, 2021, 10.21203/rs.3.rs-722605
  • Serum parathyroid hormone and 25-hydroxyvitamin D concentrations before and after biliopancreatic diversion, Gagnon, C., Hould, F.-S., Marceau, S., Biertho, L., Lebel, S., Douville, P., Julien, A.-S., Blais, J.-P., Tardio, V., Obesity Surgery, 2018, 10.1007/s11695-017-3101-z
  • Correction: Trimester-specific dietary intakes in a sample of french-canadian pregnant women in comparison with national nutritional guidelines. (Nutrients 2018, 10, 768), Robitaille, J., Morisset, A.-S., Gagnon, C., Fontaine-Bisson, B., Weisnagel, S.J., Lemieux, S., Savard, C., Nutrients, 2019, 10.3390/nu11010084
  • Measurement of bioactive osteocalcin in humans using a novel immunoassay reveals association with glucose metabolism and β-cell function, Ferron, M., Jiang, W., Gagnon, C., Karsenty, G., Rabasa-Lhoret, R., Prud'homme, D., Carpentier, A.C., Biertho, L., Tchernof, A., Grenier-Larouche, T., Turcotte, A.-F., Moran, T., Loter, L., Rifai, O.A., Lacombe, J., American Journal of Physiology - Endocrinology and Metabolism, 2020, 10.1152/ajpendo.00321.2019
  • Do pregnant women eat healthier than non-pregnant women of childbearing age?, Morisset, A.-S., Lemieux, S., Lamarche, B., Robitaille, J., Gagnon, C., Carbonneau, E., Plante, A.-S., Savard, C., International Journal of Food Sciences and Nutrition, 2020, 10.1080/09637486.2020.1723499

Contribution à l'enseignement aux cycles supérieurs

Étudiant(e)s dirigé(e)s*

Depuis 2009
  • Fatimé Adam-Hassan - Maîtrise avec mémoire - En cours
  • Angela Yang - Maîtrise avec mémoire - En cours
  • Anne-Frédérique Turcotte - Maîtrise avec mémoire - 2020/01
  • Julie-Catherine Coll - Maîtrise avec mémoire - 2022/05

Encadrement d'étudiant(e)s

Direction de recherche dans les domaines suivants :

  • Épidémiologie
  • Sciences cliniques et biomédicales

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*Les supervisions d’étudiant(e)s de 1er cycle en stage de recherche et de résident(e)s aux études médicales postdoctorales seront répertoriées ultérieurement.
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