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Jacques Couet

Professeur titulaire

Jacques Couet
Jacques.Couet@fmed.ulaval.ca
Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec
Centre de recherche de l'IUCPQ
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Contribution à la recherche

Axe de recherche de l'Université Laval :

Santé et bien-être durables

Thématiques de recherche de la Faculté de médecine :

Santé cardiovasculaire, respiratoire et métabolisme

Domaines et intérêts de recherche du (de la) professeur(e) :

Santé circulatoire et respiratoire
  • Hypertrophie cardiaque
  • Insuffisance cardiaque
  • Fibrose cardiaque
  • Valves cardiaques/maladies valvulaires

Projets de recherche

  • Biological sex, sex chromosomes and heart failure - Instituts de recherche en santé du Canada - Subvention Projet, chercheur principal - 2019-10-01 au 2024-09-30
  • Stage d'été « Carrière été » - Emploi et Développement Social Canada (EDSC), chercheur principal - 2016-05-15 au 2022-06-25

Publications

  • Female rats with severe left ventricle volume overload exhibit more cardiac hypertrophy but fewer myocardial transcriptional changes than males., Couet J, Arsenault M, Roussel É, Drolet MC, Walsh-Wilkinson É, Beaumont C, Scientific reports, 2017, 10.1038/s41598-017-00855-9
  • Changes in 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase messenger ribonucleic acid, activity and protein levels during the estrous cycle in the bovine ovary., Labrie F, Pelletier G, Zhao HF, Sirard MA, Luu-The V, Dupont E, Martel C, Couët J, Endocrinology, 1990, 10.1210/endo-127-5-2141
  • Glucocorticoid regulation of proopiomelanocortin mRNA levels in rat arcuate nucleus., Pelletier G, Simard J, Couët J, Tong Y, Molecular and cellular neurosciences, 1990, 10.1016/1044-7431(90)90043-4
  • Potent antagonism between estrogens and androgens on GCDFP-15 expression and cell growth in the ZR-75-1 human breast cancer cells., Dumont M, Couët J, Petitclerc L, Zhao HF, Dauvois S, Labrie C, Hatton AC, Poulin R, Simard J, Labrie F, Annals of the New York Academy of Sciences, 1990, 10.1111/j.1749-6632.1990.tb17805.x
  • Effectiveness of beta-blockade in experimental chronic aortic regurgitation., Couet J, Arsenault M, Roussel E, Drolet MC, Gaudreau M, Lachance D, Plante E, Circulation, 2004, 10.1161/01.cir.0000141733.55236.9d
  • Testosterone deficiency reduces cardiac hypertrophy in a rat model of severe volume overload, Jacques Couet, Marie Arsenault, Jonathan Beaudoin, Geneviève Harpin, Émile Fortier, Nicolas Melançon, Élise Roussel, Marie‐Claude Drolet, Élisabeth Walsh‐Wilkinson, Catherine Beaumont, Physiological Reports, 2019, 10.14814/phy2.14088
  • Left ventricular response to sustained volume overload from chronic aortic valve regurgitation in rats., Arsenault M, Drolet MC, Dumas MP, Gaudreau M, Couet J, Plante E, Journal of cardiac failure, 2003, 10.1054/jcaf.2003.17
  • Expression of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD) and 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD) in adipose tissue., Breton N, Couet J, Rhéaume E, Zhao HF, Labrie C, Martel C, Trudel C, Luu-The V, Simard J, Labrie F, International journal of obesity, 1991
  • Comparative study of vasodilators in an animal model of chronic volume overload caused by severe aortic regurgitation., Couet J, Arsenault M, Roussel E, Champetier S, Beaudoin J, Lachance D, Plante E, Circulation. Heart failure, 2009, 10.1161/circheartfailure.108.801548
  • Conjugating self-assembling rigid rings to flexible polymer coils for the design of organic nanotubes., Biesalski M, Couet J, Soft matter, 2006, 10.1039/b611846c
  • Treatment of combined aortic regurgitation and systemic hypertension: Insights from an animal model study., Arsenault M, Drolet MC, Roussel E, Plante E, Lachance D, Gaudreau M, Couet J, American journal of hypertension, 2006, 10.1016/j.amjhyper.2006.01.021
  • Ablation of Potassium-Chloride Cotransporter Type 3 (Kcc3) in Mouse Causes Multiple Cardiovascular Defects and Isosmotic Polyuria, Paul Isenring, Richard Larivière, Jacques Couet, Marie-Claude Drolet, Rachelle Frenette-Cotton, Micheline Noël, Andrée-Anne Marcoux, Alexandre P. Garneau, PLOS ONE, 2016, 10.1371/journal.pone.0154398
  • Metabolic syndrome negatively influences disease progression and prognosis in aortic stenosis., Pibarot P, Couet J, Arsenault M, Després JP, Cartier A, Mathieu P, Dumesnil JG, Lemieux I, Briand M, Journal of the American College of Cardiology, 2006, 10.1016/j.jacc.2005.12.073
  • Sex differences in the response to angiotensin II receptor blockade in a rat model of eccentric cardiac hypertrophy, Couet J, Arsenault M, Roy È, Drolet M, Le Houillier C, Walsh-Wilkinson É, 2019, 10.7287/peerj.preprints.27650v1
  • Characterization of two mRNA species encoding human estradiol 17 beta-dehydrogenase and assignment of the gene to chromosome 17., Simard J, Gagné R, Zhao HF, Couet J, Bérubé D, Labrie C, Luu-The V, Labrie F, Journal of steroid biochemistry, 1989, 10.1016/0022-4731(89)90082-4
  • Dobutamine stress echocardiography in healthy adult male rats., Arsenault M, Couet J, Roussel E, Drolet MC, Lachance D, Plante E, Cardiovascular ultrasound, 2005, 10.1186/1476-7120-3-34
  • Reduction of caveolin 1 gene expression in lung carcinoma cell lines., Couet J, Chakir J, Boucher M, Hirabayashi H, Bélanger M, Racine C, Biochemical and biophysical research communications, 1999, 10.1006/bbrc.1999.0236
  • Cardiac reverse remodeling in a mouse model with many phenotypical features of heart failure with preserved ejection fraction: effects of modifying lifestyle, Jacques Couët, Yohan Bossé, Marie Arsenault, Dominique K. Boudreau, Geneviève Gagnon, Audrey Morin-Grandmont, Emylie-Ann Labbé, Sara-Ève Thibodeau, Élisabeth Walsh-Wilkinson, Mohamed Lamine Aidara, American Journal of Physiology-Heart and Circulatory Physiology, 2024, 10.1152/ajpheart.00462.2023
  • Rapid modulation of ovarian 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase gene expression by prolactin and human chorionic gonadotropin in the hypophysectomized rat., Labrie F, Simard J, Labrie Y, Couet J, Gagné D, Martel C, Molecular and cellular endocrinology, 1994, 10.1016/0303-7207(94)90147-3
  • Moderate exercise training improves survival and ventricular remodeling in an animal model of left ventricular volume overload., Couet J, Arsenault M, Drolet MC, Roussel E, Champetier S, Bouchard-Thomassin AA, Plante E, Lachance D, Circulation. Heart failure, 2009, 10.1161/circheartfailure.108.845487
  • [Mechanisms of shedding of a soluble form of the TSH receptor]., Milgrom E, Couet J, Misrahi M, Annales d'endocrinologie, 1997
  • Gene expression profile of mouse fibroblasts exposed to a biodegradable iron alloy for stents., Couet J, Mantovani D, Champetier S, Hermawan H, Purnama A, Acta biomaterialia, 2013, 10.1016/j.actbio.2013.02.033
  • Age and sex hormones modulate left ventricle regional response to angiotensin II in male and female mice, Jacques Couet, Marie Arsenault, Mathieu Genest, Juliette Gagnon, Sara-Ève Thibodeau, Audrey Morin-Grandmont, Mohamed Lamine Aidara, Élisabeth Walsh-Wilkinson, American Journal of Physiology-Heart and Circulatory Physiology, 2022, 10.1152/ajpheart.00044.2022
  • Combination of an antiandrogen and a 5 alpha-reductase inhibitor: a further step towards total androgen blockade?, Labrie F, Couêt J, Martel C, Li S, Trudel C, Labrie C, Endocrinology, 1991
  • Endurance training or beta-blockade can partially block the energy metabolism remodeling taking place in experimental chronic left ventricle volume overload., Couet J, Arsenault M, Lecomte R, Rousseau JA, Sarrhini O, Gascon S, Roussel É, Drolet MC, Dhahri W, Lachance D, BMC cardiovascular disorders, 2014, 10.1186/1471-2261-14-190
  • Effects of exercise in volume overload: insights from a model of aortic regurgitation., Arsenault M, Couet J, Roussel E, Bouchard-Thomassin AA, Plante E, Champetier S, Lachance D, Medicine and science in sports and exercise, 2009, 10.1249/mss.0b013e318195b938
  • Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases., Lisanti MP, Couet J, Li S, The Journal of biological chemistry, 1996, 10.1074/jbc.271.46.29182
  • Loss of OcaB Prevents Age-Induced Fat Accretion and Insulin Resistance by Altering B-Lymphocyte Transition and Promoting Energy Expenditure, Frédéric Picard, David Marsolais, Denis Richard, André Marette, Yohan Bossé, Mathieu Ferron, Mathieu Laplante, Jacques Couet, Yves Deshaies, Julie Lacombe, Julie S. Lefebvre, Marie-Claude Drolet, Pascale Blais-Lecours, Emilie Lavoie-Charland, Fernando Forato Anhê, Philippe St-Pierre, Sandrine Sallé-Lefort, Alexandre Caron, Stéphanie Miard, Sophie Carter, Diabetes, 2018, 10.2337/db17-0558
  • Fe-Mn alloys for metallic biodegradable stents: degradation and cell viability studies., Mantovani D, Couet J, Dube D, Purnama A, Hermawan H, Acta biomaterialia, 2009, 10.1016/j.actbio.2009.11.025
  • An AAV9 coding for frataxin clearly improved the symptoms and prolonged the life of Friedreich ataxia mouse models., Tremblay JP, Chikh A, Chapdelaine P, Drolet MC, Li J, Couet J, Arsenault M, Coulombe Z, Filali M, Xiao X, Gérard C, Molecular therapy. Methods & clinical development, 2014, 10.1038/mtm.2014.44
  • Sex differences in the response to angiotensin II receptor blockade in a rat model of eccentric cardiac hypertrophy, Jacques Couet, Marie Arsenault, Ève-Marie Roy, Charlie Le Houillier, Marie-Claude Drolet, Élisabeth Walsh-Wilkinson, PeerJ, 2019, 10.7717/peerj.7461
  • Interaction of a receptor tyrosine kinase, EGF-R, with caveolins. Caveolin binding negatively regulates tyrosine and serine/threonine kinase activities., Lisanti MP, Sargiacomo M, Couet J, The Journal of biological chemistry, 1997, 10.1074/jbc.272.48.30429
  • Early left ventricular remodeling in acute severe aortic regurgitation: insights from an animal model., Arsenault M, Couet J, Drolet MC, Roussel E, Plante E, Lachance D, The Journal of heart valve disease, 2008
  • Structure of two in tandem human 17 beta-hydroxysteroid dehydrogenase genes., Labrie F, Leblanc G, Couët J, Zhao HF, Lachance Y, Simard J, Labrie C, Luu-The V, Molecular endocrinology (Baltimore, Md.), 1990, 10.1210/mend-4-2-268
  • Segmental analysis by speckle-tracking echocardiography of the left ventricle response to isoproterenol in male and female mice, Jacques Couet, Marie Arsenault, Elisabeth Walsh-Wilkinson, PeerJ, 2021, 10.7717/peerj.11085
  • Distribution of 17 beta-hydroxysteroid dehydrogenase gene expression and activity in rat and human tissues., Labrie F, Simard J, Luu-The V, Couët J, Trudel C, Takahashi M, Martel C, Rhéaume E, The Journal of steroid biochemistry and molecular biology, 1992, 10.1016/0960-0760(92)90390-5
  • Assessing the biocompatibility of degradable metallic materials: state-of-the-art and focus on the potential of genetic regulation., Mantovani D, Couet J, Hermawan H, Purnama A, Acta biomaterialia, 2010, 10.1016/j.actbio.2010.02.027
  • Gene profiling of left ventricle eccentric hypertrophy in aortic regurgitation in rats: rationale for targeting the beta-adrenergic and renin-angiotensin systems., Arsenault M, Couet J, Roussel E, Plante E, Lachance D, Beaudoin J, Bojmehrani A, Champetier S, American journal of physiology. Heart and circulatory physiology, 2008, 10.1152/ajpheart.01046.2008
  • Rosiglitazone-induced heart remodelling is associated with enhanced turnover of myofibrillar protein and mTOR activation., Deshaies Y, Marette A, Arsenault M, Couet J, Guerra-Sá R, Silva ME, Pedrosa ML, Lachance D, Achouba A, Houde VP, Brûlé S, Laplante M, Festuccia WT, Journal of molecular and cellular cardiology, 2009, 10.1016/j.yjmcc.2009.04.011
  • Regulation of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase expression and activity in the hypophysectomized rat ovary: interactions between the stimulatory effect of human chorionic gonadotropin and the luteolytic effect of prolactin., Labrie F, Pelletier G, Luu-The V, Simard J, Rheaume E, Trudel C, Couet J, Dupont E, Labrie C, Martel C, Endocrinology, 1990, 10.1210/endo-127-6-2726
  • Chronic high-fat diet-induced obesity decreased survival and increased hypertrophy of rats with experimental eccentric hypertrophy from chronic aortic regurgitation., Arsenault M, Couet J, Roussel E, Drolet MC, Dhahri W, BMC cardiovascular disorders, 2014, 10.1186/1471-2261-14-123
  • Regulation of adrenal 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase expression and activity by adrenocorticotropin and corticosterone in the rat., Labrie F, Labrie C, Martel C, Couët J, Trudel C, Endocrinology, 1991, 10.1210/endo-129-4-2077
  • Angiotensin II-converting enzyme inhibition improves survival, ventricular remodeling, and myocardial energetics in experimental aortic regurgitation., Couet J, Lecomte R, Rousseau JA, Sarrhini O, Gascon S, Grenier A, Dhahri W, Drolet MC, Roussel E, Zendaoui A, Arsenault M, Circulation. Heart failure, 2013, 10.1161/circheartfailure.112.000045
  • Impact of anesthesia on echocardiographic evaluation of systolic and diastolic function in rats., Couet J, Arsenault M, Drolet MC, Roussel E, Lachance D, Plante E, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2006, 10.1016/j.echo.2006.06.011
  • Caveolin-1 is down-regulated in human lung carcinoma and acts as a candidate tumor suppressor gene., Couet J, Roussel E, Bélanger MM, Chest, 2004, 10.1378/chest.125.5_suppl.106s
  • Dissecting the interaction between nitric oxide synthase (NOS) and caveolin. Functional significance of the nos caveolin binding domain in vivo., Sessa WC, Lisanti MP, Li S, Couet J, Skidd PM, Masters BS, Martasek P, García-Cardeña G, The Journal of biological chemistry, 1997, 10.1074/jbc.272.41.25437
  • Effects of human chorionic gonadotropin (hCG) and prolactin (PRL) on 3 beta-hydroxy-5-ene-steroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD) expression and activity in the rat ovary., Labrie F, Pelletier G, Takahashi M, Luu-The V, Trudel C, Dupont E, Couët J, Labrie C, Martel C, Molecular and cellular endocrinology, 1990, 10.1016/0303-7207(90)90107-j
  • G2/M blockade by paclitaxel induces caveolin-1 expression in A549 lung cancer cells: caveolin-1 as a marker of cytotoxicity., Couet J, Bélanger MM, Roussel E, Anti-cancer drugs, 2004, 10.1097/00001813-200411000-00005
  • Effects of the loss of estrogen on the heart’s hypertrophic response to chronic left ventricle volume overload in rats, Jacques Couet, Marie Arsenault, Jonathan Beaudoin, Charlie Le Houillier, Ève-Marie Roy, Marie-Claude Drolet, Catherine Beaumont, Elisabeth Walsh-Wilkinson, PeerJ, 2019, 10.7717/peerj.7924
  • Up-regulation of caveolin expression by cytotoxic agents in drug-sensitive cancer cells., Couet J, Roussel E, Bélanger MM, Anti-cancer drugs, 2003, 10.1097/00001813-200304000-00005
  • Caveolin interaction with protein kinase C. Isoenzyme-dependent regulation of kinase activity by the caveolin scaffolding domain peptide., Ishikawa Y, Lisanti MP, Couet J, Ohno S, Ebina T, Kawabe J, Schwencke C, Yamamoto M, Oka N, The Journal of biological chemistry, 1997, 10.1074/jbc.272.52.33416
  • Angiotensin-converting enzyme inhibitor captopril prevents volume overload cardiomyopathy in experimental chronic aortic valve regurgitation., Couet J, Arsenault M, Lapointe E, Gauthier C, Roussel E, Drolet MC, Lachance D, Gaudreau M, Plante E, Canadian journal of physiology and pharmacology, 2004, 10.1139/y04-005
  • Interstitial cells from left-sided heart valves display more calcification potential than from right-sided valves: an in-vitro study of porcine valves., Couet J, Arsenault M, Drolet MC, Roussel E, Bouchard-Martel J, The Journal of heart valve disease, 2009
  • Multiple short‐chain dehydrogenases/reductases are regulated in pathological cardiac hypertrophy, Jacques Couet, Marie Arsenault, Anne‐Marie Lavigne, Marie‐Claude Drolet, Elise Roussel, FEBS Open Bio, 2018, 10.1002/2211-5463.12506
  • Effects of spironolactone treatment on an experimental model of chronic aortic valve regurgitation., Arsenault M, Couet J, Roussel E, Lachance D, Zendaoui A, The Journal of heart valve disease, 2012
  • Inhibition of adenylyl cyclase by caveolin peptides., Ishikawa Y, Lisanti MP, Couet J, Schwencke C, Toya Y, Endocrinology, 1998, 10.1210/endo.139.4.5957
  • Role of caveolin-1 in etoposide resistance development in A549 lung cancer cells., Couet J, Roussel E, Gaudreau M, Bélanger MM, Cancer biology & therapy, 2004, 10.4161/cbt.3.10.1112
  • Regulation of 3-ketosteroid reductase messenger ribonucleic acid levels and 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase activity in rat liver by sex steroids and pituitary hormones., Labrie F, Labrie Y, Trudel C, Martel C, Simard J, Couet J, Endocrinology, 1992, 10.1210/endo.131.6.1446638
  • Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo., Lisanti MP, Peters P, van Donselaar E, Kohtz DS, Couet J, Galbiati F, Engelman JA, Volonte D, Lewis RY, Scherer PE, The Journal of biological chemistry, 1997, 10.1074/jbc.272.46.29337
  • Usefulness of carvedilol in the treatment of chronic aortic valve regurgitation., Arsenault M, Couet J, Roussel E, Lachance D, Zendaoui A, Circulation. Heart failure, 2011, 10.1161/circheartfailure.110.958512
  • Sex differences in the evolution of left ventricle remodeling in rats with severe volume overload, Jacques Couet, Marie Arsenault, Marie-Claude Drolet, Elisabeth Walsh-Wilkinson, BMC Cardiovascular Disorders, 2020, 10.1186/s12872-020-01360-0
  • Purification, cloning, complementary DNA structure, and predicted amino acid sequence of human estradiol 17 beta-dehydrogenase., Bérubé D, Lagacé L, Leblanc G, Côté J, Simard J, Lachance Y, Couët J, Zhao HF, Labrie C, Luu-The V, Annals of the New York Academy of Sciences, 1990, 10.1111/j.1749-6632.1990.tb34281.x
  • Cell biology of caveolae and caveolin., Drolet MC, Roussel E, Belanger MM, Couet J, Advanced drug delivery reviews, 2001, 10.1016/s0169-409x(01)00139-9
  • Regulation of pro-gonadotropin-releasing hormone gene expression by sex steroids in the brain of male and female rats., Pelletier G, Labrie F, Couet J, Labrie C, Simard J, Dupont E, Toranzo D, Molecular endocrinology (Baltimore, Md.), 1989, 10.1210/mend-3-11-1748
  • Electroformed pure iron as a new biomaterial for degradable stents: in vitro degradation and preliminary cell viability studies., Mantovani D, Couet J, Fiset M, Purnama A, Moravej M, Acta biomaterialia, 2010, 10.1016/j.actbio.2010.01.008
  • Transcriptional Changes Associated with Long-Term Left Ventricle Volume Overload in Rats: Impact on Enzymes Related to Myocardial Energy Metabolism, Marie Arsenault, Jacques Couet, Roger Lecomte, Jacques A. Rousseau, Otman Sarrhini, Suzanne Gascon, Dominic Lachance, Wahiba Dhahri, Elisabeth Walsh-Wilkinson, Marie-Claude Drolet, Elise Roussel, BioMed Research International, 2015, 10.1155/2015/949624
  • Multihormonal regulation of dehydroepiandrosterone sulfotransferase messenger ribonucleic acid levels in adult rat liver., Labrie F, Simard J, Labrie Y, Couët J, Endocrinology, 1994, 10.1210/endo.134.4.8137732
  • Cell surface protein disulfide-isomerase is involved in the shedding of human thyrotropin receptor ectodomain., Misrahi M, Milgrom E, Saunier B, Loosfelt H, de Bernard S, Couët J, Biochemistry, 1996, 10.1021/bi961359w
  • Molecular biology and genetics of the 3 beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase gene family., Labrie F, Luu-The V, Morel Y, Rhéaume E, Trudel C, Couet J, Labrie Y, Sanchez R, Turgeon C, Mébarki F, Durocher F, Simard J, The Journal of endocrinology, 1996
  • Early responses of the left ventricle to pressure overload in Wistar rats., Arsenault M, Couet J, Breault C, Drolet MC, Plante E, Gaudreau M, Roussel E, Life sciences, 2007, 10.1016/j.lfs.2007.11.008
  • Occurrence of cytochrome P450c17 mRNA and dehydroepiandrosterone biosynthesis in the rat gastrointestinal tract., Colombo L, Labrie F, Simontacchi C, Belvedere P, Simard J, Labrie Y, Couët J, Dalla Valle L, Molecular and cellular endocrinology, 1995, 10.1016/0303-7207(95)03553-j
  • Plasma and Myocardial miRNomes Similarities and Differences during Cardiac Remodelling and Reverse Remodelling in a Murine Model of Heart Failure with Preserved Ejection Fraction, Jacques Couet, Marie Arsenault, Audrey Morin-Grandmont, Élisabeth Walsh-Wilkinson, Emylie-Ann Labbé, Sara-Ève Thibodeau, Biomolecules, 2024, 10.3390/biom14080892
  • Structure and sexual dimorphic expression of a liver-specific rat 3 beta-hydroxysteroid dehydrogenase/isomerase., Simard J, Labrie F, Couët J, Trudel C, Rheáume E, Zhao HF, Endocrinology, 1990, 10.1210/endo-127-6-3237
  • Early endothelial dysfunction in cholesterol-fed rabbits: a non-invasive in vivo ultrasound study., Arsenault M, Couet J, Battistini B, Plante E, Drolet MC, Cardiovascular ultrasound, 2004, 10.1186/1476-7120-2-10
  • Experimental aortic regurgitation in rats under echocardiographic guidance., Couet J, Drolet MC, Plante E, Arsenault M, The Journal of heart valve disease, 2002
  • Caveolin: A possible biomarker of degradable metallic materials toxicity in vascular cells, Jacques Couet, Diego Mantovani, Agung Purnama, Acta Biomaterialia, 2013, 10.1016/j.actbio.2013.04.015
  • Plasma and Myocardial miRNomes Similarities and Differences during Cardiac Remodelling and Reverse Remodelling in a Murine Model of Heart Failure with Preserved Ejection Fraction, Jacques Couet, Marie Arsenault, Audrey Morin-Grandmont, Élisabeth Walsh-Wilkinson, Emylie-Ann Labbé, Sara-Ève Thibodeau, 2024, 10.20944/preprints202406.1909.v1
  • Development of aortic valve sclerosis or stenosis in rabbits: role of cholesterol and calcium., Arsenault M, Couet J, Drolet MC, The Journal of heart valve disease, 2008
  • Gender-related differences in left ventricular remodeling in chronic severe aortic valve regurgitation in rats., Arsenault M, Couet J, Roussel E, Plante E, Lachance D, Drolet MC, The Journal of heart valve disease, 2006
  • Attenuated Mitral Leaflet Enlargement Contributes to Functional Mitral Regurgitation After Myocardial Infarction, Jonathan Beaudoin, Robert A. Levine, Joyce Bischoff, Elena Aïkawa, Philippe Pibarot, Patrick Mathieu, Marie Arsenault, Jacques Couet, Philipp Emanuel Bartko, J. Luis Guerrero, Dae-Hee Kim, Marie-Chloé Boulanger, Marie-Claude Drolet, Marine Clisson, Mark D. Handschumacher, Marc-André Bouchard, Sandra Hadjadj, Claudia Côté-Laroche, Marie-Annick Clavel, Ons Marsit, Journal of the American College of Cardiology, 2020, 10.1016/j.jacc.2019.11.039
  • Early Activation of Growth Pathways in Mitral Leaflets Exposed to Aortic Regurgitation: New Insights from an Animal Model., Beaudoin J, Pibarot P, Levine RA, Morin S, Couet J, Arsenault M, Drolet MC, Royer O, Marsit O, The Journal of heart valve disease, 2017
  • A neomutation of the thyroid-stimulating hormone receptor in a severe neonatal hyperthyroidism., Misrahi M, Milgrom E, Czernichow P, Leger J, Couet J, Polak M, de Roux N, The Journal of clinical endocrinology and metabolism, 1996, 10.1210/jcem.81.6.8964822
  • Opposite effects of prolactin and corticosterone on the expression and activity of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase in rat skin., Labrie F, Simard J, Luo S, Labrie Y, Martel C, Couet J, The Journal of investigative dermatology, 1994, 10.1111/1523-1747.ep12389663
  • Experimental aortic valve stenosis in rabbits., Couet J, Arsenault M, Drolet MC, Journal of the American College of Cardiology, 2003, 10.1016/s0735-1097(03)00090-1
  • Blockade of androstenedione-induced stimulation of androgen-sensitive parameters in the rat prostate by combination of Flutamide and 4-MA., Labrie F, Bélanger A, Labrie C, Couet J, Trudel C, Martel C, Molecular and cellular endocrinology, 1993, 10.1016/0303-7207(93)90253-g
  • A high-fructose diet worsens eccentric left ventricular hypertrophy in experimental volume overload., Arsenault M, Couet J, Drolet MC, Lachance D, Bouchard-Thomassin AA, American journal of physiology. Heart and circulatory physiology, 2010, 10.1152/ajpheart.00199.2010
  • Benefits of long-term beta-blockade in experimental chronic aortic regurgitation., Couet J, Arsenault M, Roussel E, Drolet MC, Champetier S, Lachance D, Plante E, American journal of physiology. Heart and circulatory physiology, 2008, 10.1152/ajpheart.01286.2007
  • Fenofibrate reduces cardiac remodeling and improves cardiac function in a rat model of severe left ventricle volume overload., Arsenault M, Drolet MC, Roussel É, Couet J, Dhahri W, Life sciences, 2012, 10.1016/j.lfs.2012.10.022
  • Shedding of human thyrotropin receptor ectodomain. Involvement of a matrix metalloprotease., Misrahi M, Milgrom E, Hai MT, Jolivet A, Sar S, Couet J, The Journal of biological chemistry, 1996, 10.1074/jbc.271.8.4545
  • Molecular and cellular biology of caveolae paradoxes and plasticities., Lisanti MP, Scherer PE, Okamoto T, Shengwen L, Couet J, Trends in cardiovascular medicine, 1997, 10.1016/s1050-1738(97)00001-7
  • Structure and tissue-specific expression of a novel member of the rat 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD) family. The exclusive 3 beta-HSD gene expression in the skin., Labrie F, Turgeon C, Breton N, Sanchez R, Labrie Y, Durocher F, Couet J, Simard J, The Journal of biological chemistry, 1993
  • Blockade of the acute activation of mTOR complex 1 decreases hypertrophy development in rats with severe aortic valve regurgitation, Marie Arsenault, Jacques Couet, Veronique Tu, Elise Roussel, Vincent Desbiens-Brassard, Marie-Claude Drolet, SpringerPlus, 2015, 10.1186/s40064-015-1230-1
  • A high fat/high carbohydrate diet induces aortic valve disease in C57BL/6J mice., Arsenault M, Couet J, Deshaies Y, Roussel E, Drolet MC, Journal of the American College of Cardiology, 2006, 10.1016/j.jacc.2005.09.049
  • Identification of peptide and protein ligands for the caveolin-scaffolding domain. Implications for the interaction of caveolin with caveolae-associated proteins., Lisanti MP, Ikezu T, Okamoto T, Li S, Couet J, The Journal of biological chemistry, 1997, 10.1074/jbc.272.10.6525

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Depuis 2009
  • Diwaba Carmel Teou - Maîtrise avec mémoire - En cours
  • Sara-Ève Thibodeau - Maîtrise avec mémoire - En cours
  • Emylie-Ann Labbé - Maîtrise avec mémoire - En cours
  • Wahiba Dhahri - Doctorat - 2015/05
  • Ons Marsit - Maîtrise avec mémoire - 2016/05
  • Catherine Beaumont - Maîtrise avec mémoire - 2019/01
  • Elisabeth Walsh-Wilkinson - Maîtrise avec mémoire - 2020/01
  • Mohamed Lamine Aidara - Maîtrise avec mémoire - 2023/01
  • Audrey Morin-Grandmont - Maîtrise avec mémoire - 2024/05

Encadrement d'étudiant(e)s

Direction de recherche dans les domaines suivants :

  • Médecine moléculaire
  • Sciences cliniques et biomédicales

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Disponibilité d'encadrement d'étudiant(e)s

Ce (cette) professeur(e) est présentement à la recherche d'étudiant(e)s.

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*Les supervisions d’étudiant(e)s de 1er cycle en stage de recherche et de résident(e)s aux études médicales postdoctorales seront répertoriées ultérieurement.
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