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Jonny St-Amand

Professeur titulaire

jonny.st-amand@fmed.ulaval.ca
Centre de recherche du CHU de Québec - Université Laval
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Contribution à la recherche

Projets de recherche

  • Roles of SPARC against muscle atrophy, sarcopenia and age-related metabolic disorders - Instituts de recherche en santé du Canada - Subvention Projet, chercheur principal - 2023-03-01 au 2024-02-29

Publications

  • High-fat meal-induced changes in the duodenum mucosa transcriptome, St-Amand, J., Raymond, V., Bolduc, C., Yoshioka, M., Obesity, 2008, 10.1038/oby.2008.352
  • Long-period accelerometer monitoring shows the role of physical activity in overweight and obesity, Tanaka, H., Shindo, M., Yoshitake, Y., Miyazaki, H., St-Amand, J., Higaki, Y., Higuchi, H., Yahiro, T., Ayabe, M., Yoshioka, M., International Journal of Obesity, 2005, 10.1038/sj.ijo.0802891
  • The top 10 most abundant transcripts are sufficient to characterize the organs functional specificity: Evidences from the cortex, hypothalamus and pituitary gland, St-Amand, J., Yoshioka, M., Nishida, Y., Gene, 2005, 10.1016/j.gene.2004.09.007
  • Regeneration during Obesity: An Impaired Homeostasis, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Animals, 2020, 10.3390/ani10122344
  • Adipose tissue transcriptome by serial analysis of gene expression, St.-Amand, J., Raymond, V., Labrie, C., Morissette, J., Rodrigue, M.-A., Yoshioka, M., Lafond, N., Larose, M., Bolduc, C., Obesity Research, 2004, 10.1038/oby.2004.90
  • Transcriptomic characterization of the long-term dihydrotestosterone effects in adipose tissue, St-Amand, J., Yoshioka, M., Bolduc, C., Obesity, 2007, 10.1038/oby.2007.623
  • Obese Animals as Models for Numerous Diseases: Advantages and Applications, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Medicina, 2021, 10.3390/medicina57050399
  • Coronavirus Disease 2019 (COVID-19) Crisis: Losing Our Immunity When We Need It the Most, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Biology, 2021, 10.3390/biology10060545
  • Post-Coronavirus Disease-2019 (COVID-19): Toward a Severe Multi-Level Health Crisis?, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Medical Sciences, 2021, 10.3390/medsci9040068
  • Genetic Expression between Ageing and Exercise: Secreted Protein Acidic and Rich in Cysteine as a Potential “Exercise Substitute” Antiageing Therapy, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Genes, 2022, 10.3390/genes13060950
  • Regulation of gene expression by estrogen in mammary gland of wild type and estrogen receptor alpha knockout mice, St-Amand, J., Phaneuf, D., Yoshioka, M., Aboghe, D.H., Journal of Steroid Biochemistry and Molecular Biology, 2009, 10.1016/j.jsbmb.2008.12.002
  • Transcriptome-wide identification of preferentially expressed genes in the hypothalamus and pituitary gland, Nishida, Y., Tanaka, K., Yoshioka, M., St-Amand, J., Frontiers in Endocrinology, 2012, 10.3389/fendo.2011.00111
  • Most expressed transcripts in sexual organs and other tissues, St-Amand, J., Nishida, Y., Yoshioka, M., Kouadjo, K.E., Molecular Reproduction and Development, 2008, 10.1002/mrd.20733
  • Reproducibility, bioinformatic analysis and power of the SAGE method to evaluate changes in transcriptome, St-Amand, J., Labrie, F., Snyder, E.E., Piedboeuf, B., Calvo, E., Yoshioka, M., Boivin, A., Belleau, P., Bolduc, C., Dinel, S., Nucleic Acids Research, 2005, 10.1093/nar/gni025
  • In Vitro Mimicking of Obesity-Induced Biochemical Environment to Study Obesity Impacts on Cells and Tissues, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Diseases, 2022, 10.3390/diseases10040076
  • Regulation of muscle genes by moderate exercise, St-Amand, J., Yoshioka, M., Ogawa, W., Shindo, M., Shono, N., Murakami, K., Tobina, T., Tanaka, H., Nishida, Y., International Journal of Sports Medicine, 2010, 10.1055/s-0030-1255065
  • Housekeeping and tissue-specific genes in mouse tissues, St-Amand, J., Yoshioka, M., Cadrin-Girard, J.F., Nishida, Y., Kouadjo, K.E., BMC Genomics, 2007, 10.1186/1471-2164-8-127
  • Exercise Training of Secreted Protein Acidic and Rich in Cysteine (Sparc) KO Mice Suggests That Exercise-Induced Muscle Phenotype Changes Are SPARC-Dependent, Jonny St-Amand, Mayumi Yoshioka, Aicha Melouane, Abdelaziz GHANEMI, Applied Sciences, 2020, 10.3390/app10249108
  • Mapping Genetics and Epigenetics to Explore the Pathways beyond the Correlated Ageing Phenotype, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Genes, 2022, 10.3390/genes13112169
  • Serial analysis of gene expression in the skeletal muscle of endurance athletes compared to sedentary men, St-Amand, J., Shindo, M., Snyder, E.E., Shono, N., Tanaka, H., Yoshioka, M., FASEB Journal, 2003, 10.1096/fj.02-1200com
  • Secreted Protein Acidic and Rich in Cysteine (SPARC)—Mediated Exercise Effects: Illustrative Molecular Pathways against Various Diseases, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Diseases, 2023, 10.3390/diseases11010033
  • Impact of Adiposity and Fat Distribution, Rather Than Obesity, on Antibodies as an Illustration of Weight-Loss-Independent Exercise Benefits, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Medicines, 2021, 10.3390/medicines8100057
  • Identification of cellular processes that are rapidly modulated in response to tracheal occlusion within mice lungs, Piedboeuf, B., Khan, P.A., Moulin, V., Dinel, S., Maltais, F., Tremblay, M.G., Cloutier, M., St-Amand, J., Seaborn, T., Pediatric Research, 2008, 10.1203/PDR.0b013e31815eba47
  • Feeding induced changes in the hypothalamic transcriptome, St-Amand, J., Yoshioka, M., De Giorgio, M.R., Clinica Chimica Acta, 2009, 10.1016/j.cca.2009.06.004
  • Regulation of pituitary gene expression by adrenalectomy, St-Amand, J., Tanaka, H., Bolduc, C., Ray, C.A., Yoshioka, M., Nishida, Y., Obesity, 2009, 10.1038/oby.2008.484
  • High-Fat Diet-Induced Trefoil Factor Family Member 2 (TFF2) to Counteract the Immune-Mediated Damage in Mice, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Animals, 2021, 10.3390/ani11020258
  • Erratum: Prostate-specific genes and their regulation by dihydrotestosterone (Prostate (2008) 68, (241-254)), St-Amand, J., Labrie, F., Takase, Y., Gan, L., Belleau, P., Boivin, A., Yoshioka, M., Ma, C., Prostate, 2008, 10.1002/pros.20818
  • Coronavirus Disease 2019 (COVID-19) Crisis Measures: Health Protective Properties?, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Medicines, 2021, 10.3390/medicines8090049
  • Atlas of dihydrotestosterone actions on the transcriptome of prostate in vivo, St-Amand, J., Labrie, F., Takase, Y., Gan, L., Boivin, A., Yoshioka, M., Ma, C., Prostate, 2009, 10.1002/pros.20883
  • Secreted Protein Acidic and Rich in Cysteine (Sparc) KO Leads to an Accelerated Ageing Phenotype Which Is Improved by Exercise Whereas SPARC Overexpression Mimics Exercise Effects in Mice, Jonny St-Amand, Mayumi Yoshioka, Aicha Melouane, Abdelaziz GHANEMI, Metabolites, 2022, 10.3390/metabo12020125
  • Gene-gene interaction between apolipoprotein e2 and lipoprotein lffase on plasma lipoprotein-lipid levels, Després, J.-P., Gagné, C., Lupien, P.J., Mooriani, S., Julien, P., Gaudet, D., St-Amand, J., FASEB Journal, 1996
  • Diet Impact on Obesity beyond Calories and Trefoil Factor Family 2 (TFF2) as an Illustration: Metabolic Implications and Potential Applications, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Biomolecules, 2021, 10.3390/biom11121830
  • Ageing and Obesity Shared Patterns: From Molecular Pathogenesis to Epigenetics, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Diseases, 2021, 10.3390/diseases9040087
  • Trefoil Factor Family Member 2 (TFF2) as an Inflammatory-Induced and Anti-Inflammatory Tissue Repair Factor, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Animals, 2020, 10.3390/ani10091646
  • Maximum tolerable dose of red pepper decreases fat intake independently of spicy sensation in the mouth, Kiyonaga, A., Tanaka, H., St-Amand, J., Boivin, A., Kubo, Y., Yamane, M., Ueyama, H., Imanaga, M., Yoshioka, M., British Journal of Nutrition, 2004, 10.1079/BJN20041148
  • Acute molecular mechanisms responsive to feeding and meal constitution in mesenteric adipose tissue, St-Amand, J., Yoshioka, M., Bolduc, C., Obesity, 2010, 10.1038/oby.2009.257
  • Measuring Exercise-Induced Secreted Protein Acidic and Rich in Cysteine Expression as a Molecular Tool to Optimize Personalized Medicine, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Genes, 2021, 10.3390/genes12111832
  • Does lipoprotein or hepatic lipase activity explain the protective lipoprotein profile of premenopausal women?, Lupien, P.J., Bouchard, C., Prud'homme, D., Moorjani, S., Lamarche, B., Lemieux, S., Després, J.-P., St-Amand, J., Metabolism, 1995, 10.1016/0026-0495(95)90057-8
  • Obesity as a Neuroendocrine Reprogramming, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Medicina, 2021, 10.3390/medicina57010066
  • Secreted Protein Acidic and Rich in Cysteine as A Regeneration Factor: Beyond the Tissue Repair, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Life, 2021, 10.3390/life11010038
  • Trefoil factor family member 2 (Tff2) KO mice are protected from high-fat diet-induced obesity, St-Amand, J., Richard, D., Blin, N., Shah, A.A., Cherizol, R.-G., Moreault, O., Riedl, I., Yoshioka, M., De Giorgio, M.R., Obesity, 2013, 10.1002/oby.20165
  • Reproducibility, bioinformatic analysis and power of the SAGE method to evaluate changes in transcriptome., St-Amand, J., Labrie, F., Snyder, E.E., Piedboeuf, B., Calvo, E., Yoshioka, M., Boivin, A., Belleau, P., Bolduc, C., Dinel, S., Nucleic acids research, 2005
  • Effects of dihydrotestosterone on adipose tissue measured by serial analysis of gene expression, St-Amand, J., Labrie, F., Raymond, V., Morissette, J., Labrie, C., Belleau, P., Ye, P., Yoshioka, M., Larose, M., Bolduc, C., Journal of Molecular Endocrinology, 2004, 10.1677/jme.1.01503
  • Gender difference of androgen actions on skeletal muscle transcriptone, St-Amand, J., Bolduc, C., Boivin, A., Yoshioka, M., Journal of Molecular Endocrinology, 2007, 10.1677/JME-07-0027
  • Transcriptome of Mouse Uterus by Serial Analysis of Gene Expression (SAGE): Comparison With Skeletal Muscle, Labrie, F., Raymond, V., Labrie, C., Morissette, J., Belleau, P., Yoshioka, M., St.-Amand, J., Larose, M., Molecular Reproduction and Development, 2004, 10.1002/mrd.20065
  • Effects of dihydrotestosterone on gene expression in mammary gland, St-Amand, J., Yoshioka, M., Bolduc, C., Aboghe, D.H., Journal of Steroid Biochemistry and Molecular Biology, 2008, 10.1016/j.jsbmb.2008.06.006
  • Secreted Protein Acidic and Rich in Cysteine as a Molecular Physiological and Pathological Biomarker, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Biomolecules, 2021, 10.3390/biom11111689
  • Concomitant modulation of transcripts related to fiber type determination and energy metabolism in skeletal muscle of female ovariectomized mice by estradiol injection, St-Amand, J., Yoshioka, M., Riedl, I., Journal of Steroid Biochemistry and Molecular Biology, 2010, 10.1016/j.jsbmb.2009.12.004
  • Exercise, Diet and Sleeping as Regenerative Medicine Adjuvants: Obesity and Ageing as Illustrations, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Medicines, 2022, 10.3390/medicines9010007
  • Gene expression profile of sprinter's muscle, St-Amand, J., Shindo, M., Shono, N., Tanaka, H., Yoshioka, M., International Journal of Sports Medicine, 2007, 10.1055/s-2007-965117
  • The relation of plasma triglyceride, apolipoprotein B, and high-density lipoprotein cholesterol to postheparin lipoprotein lipase activity is dependent on apolipoprotein E polymorphism, Després, J.-P., Prud'homme, D., Lupien, P.J., Moorjani, S., St-Amand, J., Metabolism: Clinical and Experimental, 1996, 10.1016/S0026-0495(96)90064-5
  • Differential gene expression analysis in ageing muscle and drug discovery perspectives, St-Amand, J., Yoshioka, M., Aubé, S., Ghanemi, A., Melouane, A., Ageing Research Reviews, 2018, 10.1016/j.arr.2017.10.006
  • Prostate-specific genes and their regulation by dihydrotestosterone, Jonny, St.-A., Fernand, L., Yasukazu, T., Lin, G., Pascal, B., André, B., Mayumi, Y., Ci, M., Prostate, 2008, 10.1002/pros.20712
  • Regulation of global gene expression by ovariectomy and estrogen in female adipose tissue, St-Amand, J., Gan, L., Yoshioka, M., Ye, P., Obesity Research, 2005, 10.1038/oby.2005.120
  • Apolipoprotein E polymorphism and the relationships of physical fitness to plasma lipoprotein-lipid levels in men and women, Després, J.-P., Lupien, P.J., Bouchard, C., Tremblay, A., Nadeau, A., Moorjani, S., Prud'homme, D., St-Amand, J., Medicine and Science in Sports and Exercise, 1999, 10.1097/00005768-199905000-00011
  • DNA Damage as a Mechanistic Link between Air Pollution and Obesity?, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Medicines, 2022, 10.3390/medicines10010004
  • Regulation of skeletal muscle transcriptome in elderly men after 6weeks of endurance training at lactate threshold intensity, St-Amand, J., Tanaka, H., Shono, N., Paradis, R., Tobina, T., Nishida, Y., Yoshioka, M., Riedl, I., Experimental Gerontology, 2010, 10.1016/j.exger.2010.08.014
  • Exercise and High-Fat Diet in Obesity: Functional Genomics Perspectives of Two Energy Homeostasis Pillars, Jonny St-Amand, Mayumi Yoshioka, Melouane Aicha, Abdelaziz GHANEMI, Genes, 2020, 10.3390/genes11080875
  • Sexually dimorphic gene expression in the hypothalamus, pituitary gland, and cortex, St.-Amand, J., Yoshioka, M., Nishida, Y., Genomics, 2005, 10.1016/j.ygeno.2005.02.013
  • Trefoil Factor Family Member 2: From a High-Fat-Induced Gene to a Potential Obesity Therapy Target, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Metabolites, 2021, 10.3390/metabo11080536
  • Secreted Protein Acidic and Rich in Cysteine as an Exercise-Induced Gene: Towards Novel Molecular Therapies for Immobilization-Related Muscle Atrophy in Elderly Patients, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Genes, 2022, 10.3390/genes13061014
  • Effects of mild-exercise training cessation in human skeletal muscle, Tanaka, H., Shono, N., Tobina, T., Nishida, Y., Yoshioka, M., St-Amand, J., European Journal of Applied Physiology, 2012, 10.1007/s00421-011-2036-7
  • Broken Energy Homeostasis and Obesity Pathogenesis: The Surrounding Concepts, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz Ghanemi, Journal of Clinical Medicine, 2018, 10.3390/jcm7110453
  • Trefoil Factor Family Member 2 Expression as an Indicator of the Severity of the High-Fat Diet-Induced Obesity, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Genes, 2021, 10.3390/genes12101505
  • Feeding regulates the expression of pancreatic genes in gastric mucosa, St-Amand, J., Yoshioka, M., De Giorgio, M.R., Journal of Obesity, 2010, 10.1155/2010/371950
  • Secreted Protein Acidic and Rich in Cysteine (SPARC) to Manage Coronavirus Disease-2019 (COVID-19) Pandemic and the Post-COVID-19 Health Crisis, Jonny St-Amand, Mayumi Yoshioka, Abdelaziz GHANEMI, Medicines, 2023, 10.3390/medicines10050032
  • A single dose of dihydrotestosterone induced a myogenic transcriptional program in female intra-abdominal adipose tissue, St-Amand, J., Yoshioka, M., De Giorgio, M.R., Journal of Steroid Biochemistry and Molecular Biology, 2010, 10.1016/j.jsbmb.2010.02.023
  • Characterization of control and immobilized skeletal muscle: An overview from genetic engineering, Sogawa, Y., Shimizu, S., Matsumoto, K., Okamura, K., St-Amand, J., FASEB Journal, 2001, 10.1096/fj.00-0150com
  • Effects of dihydrotestosterone on skeletal muscle transcriptome in mice measured by serial analysis of gene expression, St-Amand, J., Labrie, F., Ye, P., Boivin, A., Yoshioka, M., Journal of Molecular Endocrinology, 2006, 10.1677/jme.1.01964
  • Regulation of hypothalamic gene expression by glucocorticoid: Implications for energy homeostasis, St.-Amand, J., Yoshioka, M., Nishida, Y., Physiological Genomics, 2006, 10.1152/physiolgenomics.00232.2005
  • Identification of the principal transcriptional regulators for low-fat and high-fat meal responsive genes in small intestine, St-Amand, J., Calvo, E.-L., Boivin, A., Yoshioka, M., Ghanemi, A., Melouane, A., Mucunguzi, O., Nutrition and Metabolism, 2017, 10.1186/s12986-017-0221-3

Contribution à l'enseignement aux cycles supérieurs

Étudiant(e)s dirigé(e)s*

Depuis 2009
  • Aicha Melouane - Doctorat - 2020/01
  • Octave Mucunguzi - Maîtrise avec mémoire - 2020/01
*Les supervisions d’étudiant(e)s de 1er cycle en stage de recherche et de résident(e)s aux études médicales postdoctorales seront répertoriées ultérieurement.
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