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Michel Maziade

Médecin clinicien enseignant titulaire

Michel Maziade
Michel.Maziade@fmed.ulaval.ca
Centre thématique de recherche en neurosciences
VITAM – Centre de recherche en santé durable
Centre de recherche CERVO
Centre de recherche en santé durable (VITAM)
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Contribution à la recherche

Axe de recherche de l'Université Laval :

Santé et bien-être durables

Thématiques de recherche de la Faculté de médecine :

Bioinformatique / données massives (big data)
Neurosciences et santé mentale
Pédagogie des sciences de la santé
Santé des populations et pratiques optimales en santé
Soins et services de première ligne
Transfert des connaissances

Domaines et intérêts de recherche du (de la) professeur(e) :

Génétique humaine
Neurosciences, santé mentale et toxicomanies
Santé de la mère, des enfants et des adolescents
Santé des populations
Santé différentielle des sexes
Services de santé

Projets de recherche

  • Altered retinal response as a neurobiological component of the risk trajectory and of the developmental pathophysiology of major psychiatric disorders - Instituts de recherche en santé du Canada - Subvention Projet, chercheur principal - 2022-04-01 au 2027-03-31
  • Exploring the role of rare genetic variations in the risk for schizophrenia and bipolar disorder in patients from multi-affected kindreds in the Quebec founder population - Instituts de recherche en santé du Canada - Subvention Projet, chercheur principal - 2021-04-01 au 2025-03-31
  • Institut universitaire de première ligne en santé et services sociaux. - Fonds de recherche du Québec - Société et culture - Soutien aux infrastructures de recherche des Instituts et des Centres affiliés universitaires du secteur social, co-chercheur - 2014-04-01 au 2023-03-31
  • Télé-NEUROS (Nouvel Environnement Universitaire de Recherche Orchestrée en Santé mentale et cognitive: une télé initiative) - CIUSSS - CN - CIRRIS, Université Laval - Fonds internes, CIUSSS - CN - CERVO, co-chercheur - 2020-10-20 au 2021-03-31
  • Investigating electroretinography(ERG) as a new method for predicting conversion to psychosis in youth at clinical high risk. - Instituts de recherche en santé du Canada - Subvention de fonctionnement, co-chercheur - 2015-07-01 au 2020-06-30

Publications

  • Symptom dimensions as alternative phenotypes to address genetic heterogeneity in schizophrenia and bipolar disorder., Merette C, Maziade M, Chagnon Y, Roy MA, Moreau I, Bureau A, Labbe A, 2012, 10.1038/ejhg.2012.67
  • Uptrend in distress and psychiatric symptomatology in pregnant women during the coronavirus disease 2019 pandemic, Michel Maziade, Élodie Martel, Christine Drouin‐Maziade, Julia Garon‐Bissonnette, Roxanne Lemieux, Nicolas Berthelot, Acta Obstetricia et Gynecologica Scandinavica, 2020, 10.1111/aogs.13925
  • Common Childhood Determinants of Psychiatric and Cardiovascular Disorders Call for Common Prevention and Clinical Research., Paccalet T, Maziade M, 2013, 10.1001/jamapediatrics.2013.3871
  • How prevalent are anxiety disorders in schizophrenia? A meta-analysis and critical review on a significant association., Roy MA, Mérette C, Olivier D, Raymond E, Maziade M, Achim AM, 2011, 10.1093/schbul/sbp148
  • Retinal response to light in young nonaffected offspring at high genetic risk of neuropsychiatric brain disorders., Maziade M, Mérette C, Roy MA, Jomphe V, Paradis ME, Gagné AM, Hébert M, 2010, 10.1016/j.biopsych.2009.08.016
  • Informative phenotypes for genetic studies of psychiatric disorders., Palmour R, Joober R, Roy MA, Mérette C, Zwaigenbaum L, Maziade M, Szatmari P, 2007, 10.1002/ajmg.b.30426
  • Quantifying dimensions in autism: a factor-analytic study., Maziade M, Roy MA, Cayer M, Thivierge J, Bryson SE, Mérette C, Szatmari P, 2002, 10.1097/00004583-200204000-00020
  • Gene-environment interaction and behavioral disorders: a developmental perspective based on endophenotypes., D'Amato F, Maziade M, Molteni M, Marino C, Battaglia M, 2008
  • Animal models of human anxiety disorders: reappraisal from a developmental psychopathology vantage point., Battaglia M, Maziade M, Lampis V, 2011, 10.1203/PDR.0b013e318212b42e
  • Putative Risk Factors in Developmental Dyslexia: A Case-Control Study of Italian Children., Battaglia M, Brombin C, Maziade M, Cellino MR, Riva V, Quadrelli E, Simone D, Marino C, Mascheretti S, 2013
  • Defective compensation over early dysneurogenesis in schizophrenia and mood disorder, Elsa Gilbert, Thomas Paccalet, Michel Maziade, Schizophrenia Research, 2018, 10.1016/j.schres.2017.06.041
  • Chromosome 1q12-q22 linkage results in eastern Quebec families affected by schizophrenia., Mérette C, Roy MA, Fournier JP, Cliche D, Phaneuf D, Fournier A, Maziade M, 2002, 10.1002/ajmg.1616
  • Verbal and visual memory impairments among young offspring and healthy adult relatives of patients with schizophrenia and bipolar disorder: selective generational patterns indicate different developmental trajectories., Roy MA, Paradis ME, Paccalet T, Bouchard RH, Achim A, Gilbert E, Jomphe V, Marino C, Battaglia M, Cellard C, Mérette C, Rouleau N, Maziade M, 2011, 10.1093/schbul/sbq026
  • Fine motor dexterity is correlated to social functioning in schizophrenia., Roy MA, Maziade M, Mérette C, Cayer M, René L, Brassard A, Trépanier J, Emond C, Laplante L, Lehoux C, Everett J, 2003, 10.1016/S0920-9964(02)00327-4
  • An examination of the relative contribution of saturation and selective attention to memory deficits in patients with recent-onset schizophrenia and their unaffected parents., Tremblay S, Roy MA, Maziade M, Lefèbvre AA, Cellard C, 2010, 10.1037/a0018397
  • A pilot neuropsychological study of Kraepelinian and non-Kraepelinian schizophrenia., Maziade M, Mérette C, Everett J, Bouchard RH, Laplante L, Emond C, Roy MA, Lehoux C, 2003, 10.1016/S0920-9964(02)00481-4
  • Familiarity and recollection processes in patients with recent-onset schizophrenia and their unaffected parents., Roy MA, Maziade M, Rouleau N, Achim A, Tremblay S, Cellard C, Lefèbvre AA, 2010, 10.1016/j.psychres.2009.01.007
  • Schizophrenia and Bipolar Disorder: Linkage on Chromosomes 5 and 11, , 2006, 10.1038/npg.els.0005226
  • Young offspring at genetic risk of adult psychoses: the form of the trajectory of IQ or memory may orient to the right dysfunction at the right time., Mérette C, Roy MA, Gilbert E, Marino C, Gingras N, Gagnon V, Moreau I, Paccalet T, Battaglia M, Cellard C, Rouleau N, Maziade M, 2011, 10.1371/journal.pone.0019153
  • Principal components of heritability for high dimension quantitative traits and general pedigrees., Maziade M, Roy MA, Ciampi A, Labbe A, Oualkacha K, 2012, 10.2202/1544-6115.1711
  • Replication of linkage with bipolar disorder on chromosome 16p in the Eastern Quebec population., Maziade M, Chagnon YC, Jomphe V, Cliche D, Emond C, Fournier A, Bureau A, Roy MA, Mérette C, 2008, 10.1002/ajmg.b.30673
  • Facfors associated with the reliability of the best-estimate diagnostic procedure, , 1997, 10.1016/s0920-9964(97)82017-8
  • Detection of phenotype modifier genes using two-locus linkage analysis in complex disorders such as major psychosis., Maziade M, Roy MA, Chagnon YC, Fournier A, Mérette C, Croteau J, Bureau A, 2012, 10.1159/000341392
  • Shared neurocognitive dysfunctions in young offspring at extreme risk for schizophrenia or bipolar disorder in eastern quebec multigenerational families., Roy MA, Mérette C, Battaglia M, Marino C, Doré MC, Lefebvre AA, Gilbert E, Létourneau K, Boutin J, Jomphe V, Paradis ME, Boutin P, Gingras N, Rouleau N, Maziade M, 2009, 10.1093/schbul/sbn058
  • Extreme Temperament and Diagnosis, , 1990, 10.1001/archpsyc.1990.01810170077011
  • Childhood trauma and altered response of retinal neurons as an early risk endophenotype of schizophrenia and mood disorder, Michel Maziade, Alexandre Bureau, Eric Arsenault, Julia Garon-Bissonnette, Marie-Claude Boisvert, Énora Fortin-Fabbro, Nicolas Berthelot, Jasmin Ricard, Biomarkers in Neuropsychiatry, 2024, 10.1016/j.bionps.2024.100095
  • Very poor outcome schizophrenia: A pilot study, , 1997, 10.1016/s0920-9964(97)82741-7
  • A factor analysis of the Strauss and Carpenter revised outcome criteria scale: a validation of the French translation., Roy MA, Mérette C, Emond C, Trépanier J, René L, Pelletier S, Maziade M, Bouchard RH, Lehoux C, Bureau V, Poirier S, 2004, 10.1097/01.nmd.0000146880.91895.50
  • Le tempérament de l’enfant, les différences individuelles et les forces environnementales, , 1911, 10.7202/030183ar
  • The place of the retina in psychiatry: Uniting neurobiological and neurodevelopmental research with clinical research in psychiatric disorders, Steven M. Silverstein, Michel Maziade, Schizophrenia Research, 2020, 10.1016/j.schres.2020.03.028
  • Liability indicators aggregate many years before transition to illness in offspring descending from kindreds affected by schizophrenia or bipolar disorder, Michel Maziade, Nathalie Gingras, Denis Cliche, Roch-Hugo Bouchard, Daphné Lussier, Valérie Jomphe, Pierre Marquet, Nicolas Berthelot, Elsa Gilbert, Thomas Paccalet, Schizophrenia Research, 2016, 10.1016/j.schres.2016.04.038
  • Effects of phonological and semantic cuing on encoding and retrieval processes in adolescent psychosis., Rouleau N, Maziade M, Gingras N, Caza N, Doré MC, 2009, 10.1080/13803390802317567
  • Cluster analysis of cognitive deficits may mark heterogeneity in schizophrenia in terms of outcome and response to treatment., Maziade M, Paccalet T, Roy MA, Bouchard RH, Rouleau N, Emond C, Jomphe V, Mérette C, Gilbert E, 2013
  • Atomoxetine and neuropsychological function in children with attention-deficit/hyperactivity disorder: results of a pilot study., Dickson R, Davis L, Rogers A, Lee B, Rouleau N, Maziade M, 2009, 10.1089/cap.2008.0166
  • Schizophrenia patients with polydipsia and water intoxication are characterized by greater severity of psychotic illness and a more frequent history of alcohol abuse., Roy MA, Maziade M, Bouchard RH, Mérette C, Viau-Guay L, Michea R, Tremblay P, Legris G, Poirier S, 2010, 10.1016/j.schres.2009.12.036
  • A new strategy for linkage analysis under epistasis taking into account genetic heterogeneity., Maziade M, Roy MA, Chagnon YC, Fournier A, Croteau J, Mérette C, Bureau A, 2009, 10.1159/000228921
  • A protective-compensatory model may reconcile the genetic and the developmental findings in schizophrenia., Paccalet T, Maziade M, 2013, 10.1016/j.schres.2012.12.022
  • [Genetics of schizophrenia and bipolar disorder: recent success of linkage studies with evidence of specific and shared susceptibility loci]., Roy MA, Chagnon YC, Mérette C, Maziade M, 2003
  • The brain through the retina: The flash electroretinogram as a tool to investigate psychiatric disorders., Hébert M, Maziade M, Lavoie J, 2013, 10.1016/j.pnpbp.2013.09.020
  • Retinal function anomalies in young offspring at genetic risk of schizophrenia and mood disorder: The meaning for the illness pathophysiology, Michel Maziade, Pierre Marquet, Isabelle St-Amour, Isabel Moreau, Anne-Marie Gagné, Schizophrenia Research, 2020, 10.1016/j.schres.2019.06.021
  • Heterogeneity in the longitudinal courses of global functioning in children at familial risk of major psychiatric disorders: Association with trauma and familial characteristics, Michel Maziade, Marie‐Claude Boisvert, Énora Fortin‐Fabbro, Abdoulaye Dioni, Valérie Jomphe, Camille Lafrance, Jasmin Ricard, Nicolas Berthelot, Alexandre Bureau, Bipolar Disorders, 2024, 10.1111/bdi.13386
  • Chromosome 13q13-q14 locus overlaps mood and psychotic disorders: the relevance for redefining phenotype., Mérette C, Fournier A, Bureau A, Roy MA, Chagnon YC, Maziade M, 2009, 10.1038/ejhg.2008.268
  • Decomposing the autism phenotype into familial dimensions., Palmour R, Roy MA, Maziade M, Jones MB, Zwaigenbaum L, Emond C, Mérette C, Szatmari P, 2008, 10.1002/ajmg.b.30561
  • A pilot feasibility study of an extension of the acquaintanceship recruitment procedure in recent-onset psychosis., Roy MA, Maziade M, Bouchard RH, Szatmari P, Gosselin D, Viau H, Létourneau K, Lefebvre AA, Lehoux C, 2005, 10.1097/01.nmd.0000172680.18302.80
  • Follow-up of a major psychosis linkage site in 13q13-q14 reveals significant association in both case-control and family samples., Maziade M, Mérette C, Paccalet T, Roy MA, Fournier A, Croteau J, Chagnon YC, Bureau A, 2013, 10.1016/j.biopsych.2013.03.004

Contribution à l'enseignement aux cycles supérieurs

Étudiant(e)s dirigé(e)s*

Depuis 2009
  • Geneviève Gaudreau - Doctorat - 2014/01
  • Rossana Ganzola - Doctorat - 2017/01
*Les supervisions d’étudiant(e)s de 1er cycle en stage de recherche et de résident(e)s aux études médicales postdoctorales seront répertoriées ultérieurement.
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